American Journal of Hypertension

FIGURE 2

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Estrogen Deficiency-Induced Alterations of Vascular MMP-2, MT1-MMP, and TIMP-2 in Ovariectomized Rats

Kwok-Keung Lam, Pao-Yun Cheng, George Hsiao, Shu-Ying Chen, Hsin-Hsueh Shen, Mao-Hsiung Yen and Yen-Mei Lee

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Figure 2.

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Time course of changes in (a) collagen type I, (b) pro- and active MMP-2, (c) MT1-MMP, and (d) TIMP-2 protein expression in the aorta 1–12 weeks after ovariectomy (Ovx) in rats. Data are given as means plusminus s.e.m. (n = 3 for each time point). *P < 0.05 vs. sham. MMP, matrix metalloproteinase; MT1-MMP, membrane type 1-MMP; TIMP-2, tissue inhibitor of metalloproteinases-2.

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