ADVANCE ONLINE PUBLICATION

The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
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August 22 2017

Corrigendum

Corrigendum: Rural and Urban Residence During Early Life Is Associated with a Lower Risk of Inflammatory Bowel Disease: A Population-Based Inception and Birth Cohort Study Open

Eric I Benchimol, Gilaad G Kaplan, Anthony R Otley, Geoffrey C Nguyen, Fox E Underwood, Astrid Guttmann, Jennifer L Jones, Beth K Potter, Christina A Catley, Zoann J Nugent, Yunsong Cui, Divine Tanyingoh, Nassim Mojaverian, Alain Bitton, Matthew W Carroll, Jennifer deBruyn, Trevor J B Dummer, Wael El-Matary, Anne M Griffiths, Kevan Jacobson, M Ellen Kuenzig, Desmond Leddin, Lisa M Lix, David R Mack, Sanjay K Murthy, Juan Nicolás Peña Sánchez, Harminder Singh, Laura E Targownik, Maria Vutcovici and Charles N Bernstein on behalf of the Canadian Gastro-Intestinal Epidemiology Consortium

Am J Gastroenterol advance online publication, August 22, 2017; doi:10.1038/ajg.2017.271

Functional GI Disorders

Low-Dose Linaclotide (72μg) for Chronic Idiopathic Constipation: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial Open

Philip Schoenfeld MD, Brian E Lacy MD, PhD, William D Chey MD, Anthony J Lembo MD, Caroline B Kurtz PhD, David S Reasner PhD, Wieslaw Bochenek MD, Kenneth Tripp MS, Mark G Currie PhD, Susan M Fox PhD, Rick E Blakesley PhD, Christopher R O’Dea MS, Nicholas D Omniewski MPH and Michael L Hall MD

Am J Gastroenterol advance online publication, August 22, 2017; doi:10.1038/ajg.2017.230

Subject Category: Functional GI Disorders

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August 15 2017

Esophagus

Accuracy and Safety of the Cytosponge for Assessing Histologic Activity in Eosinophilic Esophagitis: A Two-Center Study

David A Katzka MD, Thomas C Smyrk MD, Jeffrey A Alexander MD, Debra M Geno, RoseMary A Beitia, Audrey O Chang, Nicholas J Shaheen MD, MPH, Rebecca C Fitzgerald MD and Evan S Dellon MD, MPH

Am J Gastroenterol advance online publication, August 15, 2017; doi:10.1038/ajg.2017.244

Functional GI Disorders

Increasing Symptoms in Irritable Bowel Symptoms With Ingestion of Galacto-Oligosaccharides Are Mitigated by α-Galactosidase Treatment

C J Tuck BND (Hons), PhD, K M Taylor MD, P R Gibson MD, FRACP, J S Barrett PhD, BSc (Biomed) (Hons), MND and J G Muir PhD, PGrad Dip (Dietetics)

Am J Gastroenterol advance online publication, August 15, 2017; doi:10.1038/ajg.2017.245

Inflammatory Bowel Disease

Dramatic Increase in Incidence of Ulcerative Colitis and Crohn’s Disease (1988–2011): A Population-Based Study of French Adolescents

Silvia Ghione MD, Hélène Sarter MS, Mathurin Fumery MD, Laura Armengol-Debeir MD, Guillaume Savoye MD, PhD, Delphine Ley MD, PhD, Claire Spyckerelle MD, Benjamin Pariente MD, PhD, Laurent Peyrin-Biroulet MD, PhD, Dominique Turck MD, PhD, Corinne Gower-Rousseau MD, PhD and The Epimad Group

Am J Gastroenterol advance online publication, August 15, 2017; doi:10.1038/ajg.2017.228

Subject Category: Inflammatory Bowel Disease

Pancreas and Biliary Tract

The Impact of Cholecystectomy After Endoscopic Sphincterotomy for Complicated Gallstone Disease

B Joseph Elmunzer MD, Mohamed Noureldin MBBS, Katherine A Morgan MD, David B Adams MD, Gregory A Coté MD, MS and Akbar K Waljee MD, MSc

Am J Gastroenterol advance online publication, August 15, 2017; doi:10.1038/ajg.2017.247

Red Section

Society Leadership and Diversity: Hail to the Women!

Anna Lok MD, DSc, FAASLD, AGAF (AASLD President), Carol A Burke MD, FACG, FASGE, AGAF, FACP (ACG President), Sheila E Crowe MD, FRCPC, FACP, FACG, AGAF (AGA President) and Karen L Woods MD, FASGE (ASGE President)

Am J Gastroenterol advance online publication, August 15, 2017; doi:10.1038/ajg.2017.261

Review

Complications of Bariatric Surgery: What You Can Expect to See in Your GI Practice

Allison R Schulman MD and Christopher C Thompson MD, MSc, FASGE, FACG AGAF

Am J Gastroenterol advance online publication, August 15, 2017; doi:10.1038/ajg.2017.241

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August 8 2017

Errata, Corrigenda and Retractions

Corrigendum: The Conversion of Planned Colonoscopy to Sigmoidoscopy and the Effect of this Practice on the Measurement of Quality Indicators FREE

Sabina Beg, Stefano Sansone, Francesco Manguso, John Schembri, Jay Patel, Mo Thoufeeq, Gareth Corbett and Krish Ragunath

Am J Gastroenterol advance online publication, August 8, 2017; doi:10.1038/ajg.2017.211

How I approach itRed Section

How I Approach It: Strategies to Combat Physician Burnout in Gastroenterology

Joseph C Anderson MD, Sheryl Pfeil MD and Christina Surawicz MD

Am J Gastroenterol advance online publication, August 8, 2017; doi:10.1038/ajg.2017.251

The American College of Gastroenterology and the 80% by 2018 Colorectal Cancer Initiative: A Multifaceted Approach to Maximize Screening Rates

Jordan J Karlitz MD, Anne-Louise B Oliphant MPP, David A Greenwald MD and Mark B Pochapin MD

Am J Gastroenterol advance online publication, August 8, 2017; doi:10.1038/ajg.2017.217

Review

Hereditary Colorectal Polyposis and Cancer Syndromes: A Primer on Diagnosis and Management

Priyanka Kanth MD, MS, Jade Grimmett MS, Marjan Champine MS, Randall Burt MD and N Jewel Samadder MD, MSc, FRCPC

Am J Gastroenterol advance online publication, August 8, 2017; doi:10.1038/ajg.2017.212

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August 1 2017

Corrigendum/Erratum

Corrigendum: ACG and CAG Clinical Guideline: Management of Dyspepsia FREE

Paul M Moayyedi, Brian E Lacy, Christopher N Andrews, Robert A Enns, Colin W Howden and Nimish Vakil

Am J Gastroenterol advance online publication, August 1, 2017; doi:10.1038/ajg.2017.238

Functional GI Disorders

Characterizing Normal Bowel Frequency and Consistency in a Representative Sample of Adults in the United States (NHANES)

Shuji Mitsuhashi BS, Sarah Ballou PhD, Zhenghui G Jiang MD, William Hirsch BS, Judy Nee MD, Johanna Iturrino MD, Vivian Cheng MS, MPH and Anthony Lembo MD

Am J Gastroenterol advance online publication, August 1, 2017; doi:10.1038/ajg.2017.213

Fecal Incontinence Is Associated With Mortality Among Older Adults With Complex Needs: An Observational Cohort Study

Hamish A Jamieson PhD, Philip J Schluter PhD, Juno Pyun, Ted Arnold PhD, Richard Scrase, Rebecca Nisbet-Abey MSc, Vincent Mor PhD, Joanne M Deely PhD and Len Gray PhD

Am J Gastroenterol advance online publication, August 1, 2017; doi:10.1038/ajg.2017.200

Liver

Idiosyncratic Drug Induced Liver Injury in African–Americans Is Associated With Greater Morbidity and Mortality Compared to Caucasians

Naga Chalasani MD, K Rajender K Reddy MD, Robert J Fontana MD, Huiman Barnhart PhD, Jiezhun Gu PhD, Paul H Hayashi MD, Jawad Ahmad MD, Andrew Stolz MD, Victor Navarro MD and Jay H Hoofnagle MD for the United States Drug Induced Liver Injury Network

Am J Gastroenterol advance online publication, August 1, 2017; doi:10.1038/ajg.2017.215

Subject Category: Liver

Review

Chronic Pancreatitis and Pancreatic Cancer Risk: A Systematic Review and Meta-analysis

Jakob Kirkegård MD, Frank Viborg Mortensen DMSc and Deirdre Cronin-Fenton PhD

Am J Gastroenterol advance online publication, August 1, 2017; doi:10.1038/ajg.2017.218

Subject Category: Clinical and Systematic Review

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July 25 2017

Inflammatory Bowel Disease

Patient and Disease Characteristics Associated With the Presence of Diabetes Mellitus in Adults With Chronic Pancreatitis in the United States

Melena D Bellin MD, MS, David C Whitcomb MD, PhD, Judah Abberbock MS, Stuart Sherman MD, Bimaljit S Sandhu MD, Timothy B Gardner MD, Michelle A Anderson MD, MSc, Michele D Lewis MD, Samer Alkaade MD, Vikesh K Singh MD, MSc, John Baillie MD, Peter A Banks MD, Darwin Conwell MD, MS, Gregory A Cote MD, Nalini M Guda MD, Thiruvengadam Muniraj MD, Gong Tang PhD, Randall E Brand MD, Andres Gelrud MD, Stephen T Amann MD, Christopher E Forsmark MD, C Mel Wilcox MD, Adam Slivka MD, PhD and Dhiraj Yadav MD, MPH

Am J Gastroenterol advance online publication, July 25, 2017; doi:10.1038/ajg.2017.181

Rural and Urban Residence During Early Life is Associated with a Lower Risk of Inflammatory Bowel Disease: A Population-Based Inception and Birth Cohort Study Open

Eric I Benchimol MD, PhD, Gilaad G Kaplan MD, MPH, Anthony R Otley MD, MSc, Geoffrey C Nguyen MD, PhD, Fox E Underwood MSc, Astrid Guttmann MDCM, MSc, Jennifer L Jones MD, MSc, Beth K Potter PhD, Christina A Catley PhD, Zoann J Nugent PhD, Yunsong Cui MSc, Divine Tanyingoh MSc, Nassim Mojaverian MSc, Alain Bitton MD, Matthew W Carroll BMed, MHSc, Jennifer deBruyn MD, MSc, Trevor J B Dummer BA, MSc, PhD, Wael El-Matary MD, MSc, Anne M Griffiths MD, Kevan Jacobson MBBCh, M Ellen Kuenzig PhD, Desmond Leddin MD, Lisa M Lix PhD, David R Mack MD, Sanjay K Murthy MD, MSc, Juan Nicolás Peña Sánchez MD, MPH, PhD, Harminder Singh MD, MPH, Laura E Targownik MD, MSHS, Maria Vutcovici MD, MSc and Charles N Bernstein MD on behalf of the Canadian Gastro-Intestinal Epidemiology Consortium

Am J Gastroenterol advance online publication, July 25, 2017; doi:10.1038/ajg.2017.208

Subject Category: Inflammatory Bowel Disease

Pancreas and Biliary Tract

Diet and Risk of Cholecystectomy: A Prospective Study Based on the French E3N Cohort

Amélie Barré MD, Gaëlle Gusto PhD, Claire Cadeau PhD, Franck Carbonnel MD, PhD and Marie-Christine Boutron-Ruault MD, PhD

Am J Gastroenterol advance online publication, July 25, 2017; doi:10.1038/ajg.2017.216

Subject Category: Pancreas/Biliary Tract

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July 18 2017

Esophagus

Long-Term Treatment of Eosinophilic Esophagitis With Swallowed Topical Corticosteroids: Development and Evaluation of a Therapeutic Concept

Thomas Greuter MD, Christian Bussmann MD, Ekaterina Safroneeva PhD, Alain M Schoepfer MD, Luc Biedermann MD, Stephan R Vavricka MD and Alex Straumann MD

Am J Gastroenterol advance online publication, July 18, 2017; doi:10.1038/ajg.2017.202

Subject Category: Esophagus

INFLAMMATORY BOWEL DISEASE

Risk of Postoperative Complications Among Inflammatory Bowel Disease Patients Treated Preoperatively With Vedolizumab

Akihiro Yamada MD, PhD, Yuga Komaki MD, Nayan Patel, Fukiko Komaki MD, Arthur S Aelvoet, Anthony L Tran, Joel Pekow MD, Sushila Dalal MD, Russell D Cohen MD, Lisa Cannon MD, Konstantin Umanskiy MD, Radhika Smith MD, Roger Hurst MD, Neil Hyman MD, David T Rubin MD and Atsushi Sakuraba MD, PhD

Am J Gastroenterol advance online publication, July 18, 2017; doi:10.1038/ajg.2017.201

Pediatrics

Prophylactic Therapy of Cyclic Vomiting Syndrome in Children: Comparison of Amitriptyline and Cyproheptadine: A Randomized Clinical Trial

Negin Badihian, Hossein Saneian MD, Shervin Badihian MD and Omid Yaghini MD

Am J Gastroenterol advance online publication, July 18, 2017; doi:10.1038/ajg.2017.194

Stomach

Ten-Day Quadruple Therapy Comprising Proton Pump Inhibitor, Bismuth, Tetracycline, and Levofloxacin is More Effective than Standard Levofloxacin Triple Therapy in the Second-Line Treatment of Helicobacter pylori Infection: A Randomized Controlled Trial

Ping-I Hsu MD, Feng-Woei Tsai MD, Sung-Shuo Kao MD, Wen-Hung Hsu MD, Jin-Shiung Cheng MD, Nan-Jing Peng MD, Kuo-Wang Tsai PhD, Huang-Ming Hu MD, Yao-Kuang Wang MD, Seng-Kee Chuah MD, Angela Chen PhD and Deng-Chyang Wu MD, PhD On behalf of the Taiwan Acid-related Disease (TARD) Study Group

Am J Gastroenterol advance online publication, July 18, 2017; doi:10.1038/ajg.2017.195

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July 11 2017

COLON/SMALL BOWEL

Long-Term Colorectal Cancer Incidence After Negative Colonoscopy in the State of Utah: The Effect of Family History

N Jewel Samadder MD, MSc, FRCPC, Lisa Pappas MS, Kenneth M Boucherr PhD, Ken R Smith PhD, Heidi Hanson PhD, Alison Fraser MS, Yuan Wan BS, Randall W Burt MD and Karen Curtin PhD

Am J Gastroenterol advance online publication, July 11, 2017; doi:10.1038/ajg.2017.193

Endoscopy

Overuse of Repeat Upper Endoscopy in the Veterans Health Administration: A Retrospective Analysis

Joel H Rubenstein MD, MS, Heiko Pohl MD, MPH, Megan A Adams MD, JD, MS, Eve Kerr MD, MPH, Robert Holleman MPH, Sandeep Vijan MD, MS, Jason A Dominitz MD, MHS, John M Inadomi MD, Dawn Provenzale MD, MS, Joseph Francis MD, MPH and Sameer D Saini MD, MS

Am J Gastroenterol advance online publication, July 11, 2017; doi:10.1038/ajg.2017.192

STOMACH

No Association Between Proton Pump Inhibitor Use and Risk of Alzheimer’s Disease

Heidi Taipale PhD, Anna-Maija Tolppanen PhD, Miia Tiihonen PhD, Antti Tanskanen Phil Lic, Jari Tiihonen MD, PhD and Sirpa Hartikainen MD, PhD

Am J Gastroenterol advance online publication, July 11, 2017; doi:10.1038/ajg.2017.196

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July 4 2017

Inflammatory Bowel Disease

Long-Term Efficacy and Safety of Cyclosporine in a Cohort of Steroid-Refractory Acute Severe Ulcerative Colitis Patients from the ENEIDA Registry (1989–2013): A Nationwide Multicenter Study

I Ordás MD, PhD, E Domènech MD, PhD, M Mañosa MD, PhD, V García-Sánchez MD, PhD, E Iglesias-Flores MD, M Peñalva MD, A Cañas-Ventura MD, O Merino MD, F Fernández-Bañares MD, PhD, F Gomollón MD, PhD, M Vera MD, PhD, A Gutiérrez MD, PhD, E Garcia-Planella MD, PhD, M Chaparro MD, PhD, M Aguas MD, PhD, E Gento MD, F Muñoz MD, M Aguirresarobe MD, C Muñoz MD, PhD, L Fernández MD, PhD, X Calvet MD, PhD, C E Jiménez MD, M A Montoro MD, PhD, A Mir MD, M L De Castro MD, PhD, M F García-Sepulcre MD, F Bermejo MD, PhD, J Panés MD, PhD and M Esteve MD, PhD on behalf of the ENEIDA registry of GETECCU

Am J Gastroenterol advance online publication, July 4, 2017; doi:10.1038/ajg.2017.180

Subject Category: Inflammatory Bowel Disease

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June 6 2017

Liver

Interferon-Free Therapy in Elderly Patients With Advanced Liver Disease

Sabela Lens MD, Inmaculada Fernández MD, Sergio Rodríguez-Tajes MD, Vanessa Hontangas MD, Mercedes Vergara MD, Montserrat Forné MD, Jose Luis Calleja MD, Moisés Diago MD, Jordi Llaneras MD, Susana Llerena MD, Xavier Torras MD, Begoña Sacristán MD, Merce Roget MD, Conrado Manuel Fernández-Rodríguez MD, Mari Carmen Navascués MD, Javier Fuentes MD, Juan- José Sánchez-Ruano MD, Miguel-Ángel Simón MD, Federico Sáez-Royuela MD, Carmen Baliellas MD, Rosa Morillas MD, Xavier Forns MD and for the Spanish Group for the Study of the Use of Direct-acting Drugs Hepatitis C Collaborating Group

Am J Gastroenterol advance online publication, June 6, 2017; doi:10.1038/ajg.2017.157

Subject Category: Liver

Review

Beneficial Effects of Statins on the Rates of Hepatic Fibrosis, Hepatic Decompensation, and Mortality in Chronic Liver Disease: A Systematic Review and Meta-Analysis

Sehrish Kamal MD, Muhammad Ali Khan MD, Ankur Seth MD, George Cholankeril MD, Deepansh Gupta MD, Utkarsh Singh MD, Faisal Kamal MD, Colin W Howden MD, FACG, Christopher Stave MLS, Satheesh Nair MD, Sanjaya K Satapathy MD, FACG and Aijaz Ahmed MD

Am J Gastroenterol advance online publication, June 6, 2017; doi:10.1038/ajg.2017.170

Subject Category: Clinical and Systematic Review

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May 30 2017

Endoscopy

The Conversion of Planned Colonoscopy to Sigmoidoscopy and the Effect of this Practice on the Measurement of Quality Indicators

Sabina Beg MBBS, MRCP, Stefano Sansone MD, Francesco Manguso MD, PhD, John Schembri MD, MRCP, Jay Patel MBBS, MRCP, Mo Thoufeeq MBBS, MRCP, Gareth Corbett MBBS, MRCP and Krish Ragunath MD, FRCP

Am J Gastroenterol advance online publication, May 30, 2017; doi:10.1038/ajg.2017.138

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May 16 2017

Pediatrics

Influence of Age and Eosinophilic Esophagitis on Esophageal Distensibility in a Pediatric Cohort

Calies Menard-Katcher MD, MS, Alain J Benitez MD, Zhaoxing Pan PhD, Faria N Ahmed BA, Benjamin J Wilkins MD, PhD, Kelley E Capocelli MD, Chris A Liacouras MD, Ritu Verma MD, Jonathan M Spergel MD, PhD, Glenn T Furuta MD and Amanda B Muir MD, PhD

Am J Gastroenterol advance online publication, May 16, 2017; doi:10.1038/ajg.2017.131

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April 25 2017

Liver

The Natural History of Severe Acute Liver Injury

David G Koch MD, MSCR, J L Speiser, V Durkalski, R J Fontana MD, T Davern MD, B McGuire MD, R T Stravitz MD, A M Larson MD, I Liou, O Fix MD, M L Schilsky MD, T McCashland MD, J E Hay MD, N Murray MD, O S Shaikh MD, D Ganger MD, A Zaman MD, S B Han MD, R T Chung MD, R S Brown MD, S Munoz MD, K R Reddy, L Rossaro MD, R Satyanarayana, A J Hanje MD, J Olson MD, R M Subramanian MD, C Karvellas MD, B Hameed MD, A H Sherker MD, W M Lee MD and A Reuben MD the Acute Liver Failure Study Group

Am J Gastroenterol advance online publication, April 25, 2017; doi:10.1038/ajg.2017.98

Subject Category: Liver

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April 4 2017

Pancreas and Biliary Tract

Autoimmune Pancreatitis in Children: Characteristic Features, Diagnosis, and Management

Isabelle Scheers MD, PhD, Joseph J Palermo MD, PhD, Steven Freedman MD, PhD, Michael Wilschanski MD, Uzma Shah MD, Maisam Abu-El-Haija MD, Bradley Barth MD, MPH, Douglas S Fishman MD, Cheryl Gariepy MD, Matthew J Giefer MD, Melvin B Heyman MD, MPH, Ryan W Himes MD, Sohail Z Husain MD, Tom K Lin MD, Quin Liu MD, Mark Lowe MD, PhD, Maria Mascarenhas MD, Veronique Morinville MD, Chee Y Ooi MD, PhD, Emily R Perito MD, David A Piccoli MD, John F Pohl MD, Sarah J Schwarzenberg MD, David Troendle MD, Steven Werlin MD, Bridget Zimmerman PhD, Aliye Uc MD and Tanja Gonska MD

Am J Gastroenterol advance online publication, April 4, 2017; doi:10.1038/ajg.2017.85

Subject Category: Pancreas/Biliary Tract

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January 10 2017

Inflammatory Bowel Disease

Responsiveness of Endoscopic Indices of Disease Activity for Crohn’s Disease

Reena Khanna MD, GuangYong Zou PhD, Larry Stitt MSc, Brian G Feagan MD, William J Sandborn MD, Paul Rutgeerts MD, PhD, John W D McDonald MD, Elena Dubcenco MD, Ronald Fogel MD, Remo Panaccione MD, Vipul Jairath MD, PhD, Sigrid Nelson MSc, Lisa M Shackelton PhD, Bidan Huang PhD, Qian Zhou PhD, Anne M Robinson, Barrett G Levesque MD and Geert D'Haens MD, PhD

Am J Gastroenterol advance online publication, January 10, 2017; doi:10.1038/ajg.2016.580

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