¹The Departments of Gastroenterology, Infectious Disease, and Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, Ohio, USA

Correspondence: John A Dumot, DO, Gastroenterology-S40, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195

Received 26 March 1998; Revised  0000; Accepted 29 May 1998.

Abstract

Sarcoidosis presenting solely as a granulomatous colitis is rare and appears identical to Crohn's disease. A 56-yr-old woman developed a Crohn's-like illness, which remitted after 5-ASA therapy. Two months later, she developed fever, adenopathy, muscle weakness, and peripheral neuropathy. A diagnosis of sarcoidosis was made after an extensive search for an infectious or rheumatological cause. This case illustrates the utility of serum angiotensin converting enzyme level in differentiating sarcoidosis from Crohn's disease.