TABLE OF CONTENTS

Volume 111, Issue 1 (January 2016)

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The Red Section

The American Journal of Gastroenterology in 2016: Where Have We Been? Where Are We Going?

Brian E Lacy PhD, MD, FACG and Brennan Spiegel MD, MSHS, FACG

Am J Gastroenterol 111: 1-3; advance online publication, January 12, 2016; doi:10.1038/ajg.2015.407

Welcome to the New Red Section

Hetal A Karsan MD, FACG (co-editor, Red Section) and Sameer D Saini MD, MS (co-editor, Red Section)

Am J Gastroenterol 111: 4-5; advance online publication, January 12, 2016; doi:10.1038/ajg.2015.411

Just Clip It: Endoscopic Clipping in the 21st Century

B Joseph Elmunzer MD

Am J Gastroenterol 111: 6-8; advance online publication, January 5, 2016; doi:10.1038/ajg.2015.382

How I Approach Retroflexion and Prevention of Right-Sided Colon Cancer Following Colonoscopy

Douglas K Rex MD, MACG

Am J Gastroenterol 111: 9-11; advance online publication, January 12, 2016; doi:10.1038/ajg.2015.385

Gluten Introduction, Breastfeeding, and Celiac Disease: Back to the Drawing Board

Benjamin Lebwohl MD, MS, Joseph A Murray MD, Elena F Verdú MD, PhD, Sheila E Crowe MD, Melinda Dennis RD, Alessio Fasano MD, Peter H R Green MD, Stefano Guandalini MD and Chaitan Khosla PhD

Am J Gastroenterol 111: 12-14; advance online publication, August 11, 2015; doi:10.1038/ajg.2015.219

Health Insurance Paid Costs and Drivers of Costs for Patients With Crohn’s Disease in the United States

K T Park MD, MS, Richard B Colletti MD, David T Rubin MD, Bal K Sharma PhD, Amy Thompson MBA and Andrew Krueger MD

Am J Gastroenterol 111: 15-23; advance online publication, July 21, 2015; doi:10.1038/ajg.2015.207

Images of the Month

Vascular Anomaly of Blue Rubber Bleb Nevus Syndrome

Tyler Aasen, Yousef Usta, Houry Achdjian, Rakesh Nanda and Aaron Goldberg

Am J Gastroenterol 111: 24; doi:10.1038/ajg.2015.196

An Unusual Cause of Umbilical Nodule

Vishal Sharma, Surinder Singh Rana and Deepak Kumar Bhasin

Am J Gastroenterol 111: 24; doi:10.1038/ajg.2015.224

Endoscopic Appearance of Rectal Spread of Squamous Cell Carcinoma

Brandon Sprung, Michael D Lunt, Christa Whitney-Miller and Arthur J DeCross

Am J Gastroenterol 111: 25; doi:10.1038/ajg.2015.193

Leg Ulcer in Budd-Chiari syndrome

Xingshun Qi and Guohong Han

Am J Gastroenterol 111: 25; doi:10.1038/ajg.2015.177

A Rare Case of Hyperpigmentation of the Duodenum

Mohamad H Imam, Hong Peng and Sajid Jalil

Am J Gastroenterol 111: 26; doi:10.1038/ajg.2015.175

Chilaiditi Syndrome

Juan E Corral, Seth Sclair and Baharak Moshiree

Am J Gastroenterol 111: 26; doi:10.1038/ajg.2015.195

Endoscopic Pitfalls: Adult Unrepaired Cleft Palate

Mohammad Bilal and Kofi Clarke

Am J Gastroenterol 111: 27; doi:10.1038/ajg.2015.236

Severe Portal Hypertension–Inducted Anorectal Varices Bleeding Treated via a Transjugular Intrahepatic Portosystemic Shunt

Yen-Hsiu Liao, Wei-Tse Hsia, Chen Yung-Fang and Po-Pang Tsai

Am J Gastroenterol 111: 27; doi:10.1038/ajg.2015.264

Video of the Month

Kirbylee K Nelson, Steven B Clayton and Joel E Richter

Am J Gastroenterol 111: 28; doi:10.1038/ajg.2015.303

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Practice Guidelines

Continuing Medical Education: January 2016

Am J Gastroenterol 111: 29; doi:10.1038/ajg.2015.410

Continuing Medical Education ACG Clinical Guideline: Diagnosis and Management of Barrett’s Esophagus FREE

Nicholas J Shaheen MD, MPH, FACG, Gary W Falk MD, MS, FACG, Prasad G Iyer MD, MSc, FACG and Lauren B Gerson MD, MSc, FACG

Am J Gastroenterol 111: 30-50; advance online publication, November 3, 2015; doi:10.1038/ajg.2015.322

Continuing Medical Education Questions: January 2016

Renu Umashanker MD, FACG

Am J Gastroenterol 111: 51; doi:10.1038/ajg.2015.414

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Clinical and Systematic Reviews

Review

Continuing Medical Education: January 2016

Am J Gastroenterol 111: 52; doi:10.1038/ajg.2015.415

Subject Category: Clinical and Systematic Review

Continuing Medical Education Diagnosis and Management of Functional Heartburn

Christine Hachem MD and Nicholas J Shaheen MD, MPH

Am J Gastroenterol 111: 53-61; advance online publication, January 5, 2016; doi:10.1038/ajg.2015.376

Subject Category: Clinical and Systematic Review

Continuing Medical Education Questions: January 2016

Christine Y Hachem MD, FACG

Am J Gastroenterol 111: 62; doi:10.1038/ajg.2015.416

Subject Category: Clinical and Systematic Review

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Original Contributions

Endoscopy

Effect of Dynamic Position Changes on Adenoma Detection During Colonoscope Withdrawal: A Randomized Controlled Multicenter Trial

Seung-Woo Lee MD, PhD, Jae Hyuck Chang MD, PhD, Jeong-Seon Ji MD, PhD, Il Ho Maeong MD, Dae Young Cheung MD, PhD, Joon Sung Kim MD, Young-Seok Cho MD, PhD, Wook-Jin Chung MD, PhD, Bo-In Lee MD, PhD, Sang-Woo Kim MD, PhD, Byung-Wook Kim MD, PhD, Hwang Choi MD, PhD and Myung-Gyu Choi MD, PhD

Am J Gastroenterol 111: 63-69; advance online publication, November 3, 2015; doi:10.1038/ajg.2015.354

Subject Category: Endoscopy

Liver

Application of the Intermediate-Stage Subclassification to Patients With Untreated Hepatocellular Carcinoma

Edoardo G Giannini MD, PhD, FACG, Alessandro Moscatelli MD, Gaia Pellegatta MD, Alessandro Vitale MD, Fabio Farinati MD, Francesca Ciccarese MD, Fabio Piscaglia MD, Gian Lodovico Rapaccini MD, Maria Di Marco MD, Eugenio Caturelli MD, Marco Zoli MD, Franco Borzio MD, Giuseppe Cabibbo MD, Martina Felder MD, Rodolfo Sacco MD, Filomena Morisco MD, Gabriele Missale MD, Francesco Giuseppe Foschi MD, Antonio Gasbarrini MD, Gianluca Svegliati Baroni MD, Roberto Virdone MD, Alberto Masotto, Franco Trevisani MD and for the Italian Liver Cancer (ITA.LI.CA) Group

Am J Gastroenterol 111: 70-77; advance online publication, January 5, 2016; doi:10.1038/ajg.2015.389

Subject Category: Liver

Diagnosis of Minimal Hepatic Encephalopathy Using Stroop EncephalApp: A Multicenter US-Based, Norm-Based Study

Sanath Allampati MD, Andres Duarte-Rojo MD, Leroy R Thacker PhD, Kavish R Patidar MD, Melanie B White RN, Jagpal S Klair MD, Binu John MD, Douglas M Heuman MD, James B Wade PhD, Christopher Flud MD, Robert O’Shea MD, Edith A Gavis RN, Ariel B Unser BS and Jasmohan S Bajaj MD

Am J Gastroenterol 111: 78-86; advance online publication, December 8, 2015; doi:10.1038/ajg.2015.377

Subject Category: Liver

Could Adherence to Quality of Care Indicators for Hospitalized Patients With Cirrhosis-Related Ascites Improve Clinical Outcomes?

Suong Le MBBS, FRACP, MClinResMeth, Tim Spelman MBBS, FRACP, PhD, Chia-Pei Chong MBBS, Phil Ha MBBS (Hons), BMedSc, Lukas Sahhar BMedSc (Hons), Julian Lim MBBS (Hons), BMedSc, Tony He MBBS (Hons), Neel Heerasing MBBS, FRACP and William Sievert MD, FRACP

Am J Gastroenterol 111: 87-92; advance online publication, January 5, 2016; doi:10.1038/ajg.2015.402

Subject Category: Liver

Functional GI Disorders

The Epidemiology of Irritable Bowel Syndrome in the US Military: Findings from the Millennium Cohort Study Open

Mark S Riddle MD, DrPH, Marleen Welsh PhD, Chad K Porter MPH, PhD, Chiping Nieh PhD, Edward J Boyko MD, MPH, Gary Gackstetter DVM, PhD and Tomoko I Hooper MD, MPH, PhD

Am J Gastroenterol 111: 93-104; advance online publication, January 5, 2016; doi:10.1038/ajg.2015.386

Subject Category: Functional GI Disorders

Colon/Small Bowel

Adherence to Competing Strategies for Colorectal Cancer Screening Over 3 Years

Peter S Liang MD, MPH, Chelle L Wheat MPH, Anshu Abhat MD, MPH, Alison T Brenner PhD, Angela Fagerlin PhD, Rodney A Hayward MD, Jennifer P Thomas BS, Sandeep Vijan MD, MS and John M Inadomi MD

Am J Gastroenterol 111: 105-114; advance online publication, November 3, 2015; doi:10.1038/ajg.2015.367

Subject Category: Colon/Small Bowel

Prevalence of Adult Celiac Disease in India: Regional Variations and Associations

B S Ramakrishna DM, PhD, Govind K Makharia DM, Kamal Chetri DM, Sangitanjan Dutta DM, Prashant Mathur MD, Vineet Ahuja DM, Ritvik Amarchand MBBS, PhD, Ramadass Balamurugan PhD, Sudipta D Chowdhury DM, Dolly Daniel MD, Anup Das MD, Gemlyn George MBBS, Siddhartha Datta Gupta MD, Anand Krishnan MD, Jasmin H Prasad MD, Gurvinder Kaur PhD, Srinivasan Pugazhendhi PhD, Anna Pulimood MD, PhD, Kartik Ramakrishna MBBS and Anil K Verma MSc

Am J Gastroenterol 111: 115-123; advance online publication, January 5, 2016; doi:10.1038/ajg.2015.398

Subject Category: Colon/Small Bowel

Pediatrics

A Prospective Study on the Usefulness of Duodenal Bulb Biopsies in Celiac Disease Diagnosis in Children: Urging Caution

Juha Taavela MD, Alina Popp MD, Ilma Rita Korponay-Szabo MD, Adina Ene MD, Martine Vornanen MD, Päivi Saavalainen PhD, Marja-Leena Lähdeaho MD, Tarja Ruuska MD, Kaija Laurila MSc, Alexandru Parvan MD, Ioana Anca MD, Kalle Kurppa MD and Markku Mäki MD

Am J Gastroenterol 111: 124-133; advance online publication, January 5, 2016; doi:10.1038/ajg.2015.387

Subject Category: Pediatrics

In the Intestinal Mucosa of Children With Potential Celiac Disease IL-21 and IL-17A are Less Expressed than in the Active Disease

Melissa Borrelli PhD, Carmen Gianfrani MS, Giuliana Lania PhD, Rosita Aitoro PhD, Katia Ferrara MD, Merlin Nanayakkara PhD, Domenico Ponticelli MD, Delia Zanzi MS, Valentina Discepolo PhD, Serena Vitale MS, Maria Vittoria Barone MD, Riccardo Troncone MD, Renata Auricchio and Mariantonia Maglio

Am J Gastroenterol 111: 134-144; advance online publication, January 12, 2016; doi:10.1038/ajg.2015.390

Subject Category: Pediatrics

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Letters to the Editor

Intraluminal pH As a Pathophysiological Biomarker of Fermentation in Irritable Bowel Syndrome

Adam D Farmer PhD, MRCP and Anthony R. Hobson PhD

Am J Gastroenterol 111: 145; doi:10.1038/ajg.2015.394

See also: Letter to the Editor by Choi et al.

“Gährungsdyspepsie” Revisited

Jørgen Valeur MD, PhD, Ragnhild Undseth MD and Arnold Berstad MD, PhD

Am J Gastroenterol 111: 145-147; doi:10.1038/ajg.2015.361

See also: Letter to the Editor by Choi et al.

Response to Valeur et al. and Farmer et al.

Chang Hwan Choi MD, PhD, Tamar Ringel-Kulka MD, MPH and Yehuda Ringel MD, AGAF, FACG,

Am J Gastroenterol 111: 147-148; doi:10.1038/ajg.2015.409

See also: Letter to the Editor by FarmerSee also: Letter to the Editor by Valeur et al.

Harvoni (Ledipasvir With Sofosbuvir)-Induced Renal Injury

Rimda Wanchoo MD, Jyotsana Thakkar MD, Daniel Schwartz MD and Kenar D Jhaveri MD

Am J Gastroenterol 111: 148-149; doi:10.1038/ajg.2015.391

Elevated Serum Triglycerides Associated With Systemic Inflammatory Response Syndrome and Persistent Organ Failure in Acute Pancreatitis

Emmanuel I González-Moreno MD, José A González-González MD, Elvira Garza-González PhD, Francisco J Bosques-Padilla MD, PhD and Héctor J Maldonado-Garza MD, PhD

Am J Gastroenterol 111: 149; doi:10.1038/ajg.2015.388

Azathioprine May Not be Associated With Development of Colorectal Tumors With Microsatellite Instability in Patients With Inflammatory Bowel Disease

Magali Svrcek MD, PhD, Laurent Beaugerie MD, PhD, Julien Kirchgesner MD, Sylvie Dumont MSc, Martine Muleris PhD, Sahra Bodo PhD, Peggy Dartigues MD, Olivier Lascols MD, PhD, Philippe Seksik MD, PhD, Jacques Cosnes MD, PhD, Jean- François Fléjou MD, PhD and Alex Duval MD, PhD for the CESAME study group

Am J Gastroenterol 111: 149-151; doi:10.1038/ajg.2015.406

ATG7 Gene Expression as a Novel Tissue Biomarker in Eosinophilic Esophagitis

Jamie F Merves MD, Kelly A Whelan PhD, Alain J Benitez MD, Amanda B Muir MD, Glenn T Furuta MD, Mei-Lun Wang MD, Gary W Falk MD, MS, Jonathan M Spergel MD, PhD and Hiroshi Nakagawa MD, PhD

Am J Gastroenterol 111: 151-153; doi:10.1038/ajg.2015.404

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Announcements

Calendar of Courses, Symposiums, and Conferences

Am J Gastroenterol 111: 154; doi:10.1038/ajg.2015.384

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Errata, Corrigenda, Retractions and Addenda

Erratum: Successful Delayed Endoscopic Closure of an Iatrogenic Perforation FREE

Alejandro L Suarez, Molly C Mcvey and B Joseph Elmunzer

Am J Gastroenterol 111: 155; doi:10.1038/ajg.2015.396