TABLE OF CONTENTS

Volume 108, Issue 5 (May 2013)

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The Red Section

Self-Reported Food-Related Gastrointestinal Symptoms in IBS Are Common and Associated With More Severe Symptoms and Reduced Quality of Life

Lena Böhn RD, Stine Störsrud RD, PhD, Hans Törnblom MD, PhD, Ulf Bengtsson MD, PhD and Magnus Simrén MD, PhD

Am J Gastroenterol 108: 634-641; doi:10.1038/ajg.2013.105

What Gastroenterologists Should Know About the Gray Market, Herbal Remedies, and Compounded Pharmaceuticals and Their Regulation by the Food and Drug Administration

Eli D. Ehrenpreis MD, Prasad Kulkarni MD, Carol Burke MD and the FDA-Related Matters Committee of the American College of Gastroenterology

Am J Gastroenterol 108: 642-646; doi:10.1038/ajg.2012.348

Villous Atrophy and Negative Celiac Serology: A Diagnostic and Therapeutic Dilemma

Marisa DeGaetani MD, Christina A Tennyson MD, Benjamin Lebwohl MD, MS, Suzanne K Lewis MD, Hussein Abu Daya MD, PhD, Carolina Arguelles-Grande MD, Govind Bhagat MBBS and Peter H R Green MD

Am J Gastroenterol 108: 647-653; doi:10.1038/ajg.2013.45

Images of the Month

Am J Gastroenterol 108: 654; doi:10.1038/ajg.2013.106

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Practice Guidelines

Continuing Medical Education: May 2013

Am J Gastroenterol 108: 655; doi:10.1038/ajg.2013.114

Continuing Medical Education ACG Clinical Guidelines: Diagnosis and Management of Celiac Disease

Alberto Rubio-Tapia MD, Ivor D Hill MD, Ciarán P Kelly MD, Audrey H Calderwood MD and Joseph A Murray MD

Am J Gastroenterol 108: 656-676; advance online publication, April 23, 2013; doi:10.1038/ajg.2013.79

Continuing Medical Education Questions: May 2013

Kenneth R DeVault MD, FACG, Lindsay Crabbe MD, Amreen Dinani MD and Zain Kassam MD

Am J Gastroenterol 108: 677; doi:10.1038/ajg.2013.115

Continuing Medical Education: May 2013

Am J Gastroenterol 108: 678; doi:10.1038/ajg.2013.116

Continuing Medical Education ACG Clinical Guideline: Evidenced Based Approach to the Diagnosis and Management of Esophageal Eosinophilia and Eosinophilic Esophagitis (EoE)

Evan S Dellon MD, MPH, Nirmala Gonsalves MD, Ikuo Hirano MD, FACG, Glenn T Furuta MD, Chris A Liacouras MD and David A Katzka MD, FACG

Am J Gastroenterol 108: 679-692; advance online publication, April 9, 2013; doi:10.1038/ajg.2013.71

Continuing Medical Education Questions: May 2013

Kenneth R DeVault MD, FACG, Arthi Kumaravel MD, Carole Macaron MD, Mazen Albeldawi MD and Paresh Mehta MD

Am J Gastroenterol 108: 693; doi:10.1038/ajg.2013.117

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Role of Food in Functional Gastrointestinal Disorders

Rome Foundation Working Group

The Role of Food in the Functional Gastrointestinal Disorders: Introduction to a Manuscript Series

William D Chey MD, AGAF, FACG, FACP

Am J Gastroenterol 108: 694-697; advance online publication, April 2, 2013; doi:10.1038/ajg.2013.62

Food and Symptom Generation in Functional Gastrointestinal Disorders: Physiological Aspects

Ricard Farré PhD and Jan Tack MD, PhD

Am J Gastroenterol 108: 698-706; advance online publication, March 5, 2013; doi:10.1038/ajg.2013.24

Short-Chain Carbohydrates and Functional Gastrointestinal Disorders

Susan J Shepherd BAppSci, MND, PhD, Miranda C E Lomer RD, PhD and Peter R Gibson MD, FRACP

Am J Gastroenterol 108: 707-717; advance online publication, April 16, 2013; doi:10.1038/ajg.2013.96

Fiber and Functional Gastrointestinal Disorders

Shanti Eswaran MD, Jane Muir PhD and William D Chey MD, AGAF, FACG, FACP

Am J Gastroenterol 108: 718-727; advance online publication, April 2, 2013; doi:10.1038/ajg.2013.63

Dietary Proteins and Functional Gastrointestinal Disorders

Erica Boettcher MD and Sheila E Crowe MD

Am J Gastroenterol 108: 728-736; advance online publication, April 9, 2013; doi:10.1038/ajg.2013.97

Dietary Lipids and Functional Gastrointestinal Disorders

Christine Feinle-Bisset PhD and Fernando Azpiroz MD, PhD

Am J Gastroenterol 108: 737-747; advance online publication, April 9, 2013; doi:10.1038/ajg.2013.76

Design of Clinical Trials Evaluating Dietary Interventions in Patients With Functional Gastrointestinal Disorders

Chu K Yao BND (Hons), Peter R Gibson MD, FRACP and Susan J Shepherd PhD, MND, BAppSci

Am J Gastroenterol 108: 748-758; advance online publication, April 23, 2013; doi:10.1038/ajg.2013.77

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Original Contributions

Esophagus

Elemental Diet Induces Histologic Response in Adult Eosinophilic Esophagitis

Kathryn A Peterson MD, MSc(Epid), Kathryn R Byrne MD, Laura A Vinson MS, Jian Ying PhD, Kathleen K Boynton MD, John C Fang MD, Gerald J Gleich MD, Douglas G Adler MD and Frederic Clayton MD

Am J Gastroenterol 108: 759-766; advance online publication, February 5, 2013; doi:10.1038/ajg.2012.468

Subject Category: Esophagus

Stomach

Symptom Overlap Between Postprandial Distress and Epigastric Pain Syndromes of the Rome III Dyspepsia Classification

Nimish Vakil MD, FACG, Katarina Halling MSc, Lis Ohlsson MSc and Börje Wernersson BSc

Am J Gastroenterol 108: 767-774; advance online publication, April 9, 2013; doi:10.1038/ajg.2013.89

See also: Original Contribution by Talley et al.

Subject Category: Stomach

Editorial: Functional (Non-Ulcer) Dyspepsia and Gastroesophageal Reflux Disease: One Not Two Diseases?

Nicholas J Talley MD, PhD

Am J Gastroenterol 108: 775-777; doi:10.1038/ajg.2013.102

See also: Original Contribution by Vakil et al.

Subject Category: Stomach

Liver

The Western Dietary Pattern Is Prospectively Associated With Nonalcoholic Fatty Liver Disease in Adolescence

Wendy H Oddy BAppSci, MPH, PhD, Carly E Herbison BSc (Hons), Peter Jacoby BA, MSc, Gina L Ambrosini BAppSci, MPH, PhD, Therese A O'Sullivan BHlthSci, BAppSci, PhD, Oyekoya T Ayonrinde MBBS, FRACP, John K Olynyk MBBS, FRACP, MD, Lucinda J Black BSc, PhD, Lawrence J Beilin MBBS, FRCP, FRACP, FCSANZ, MD, Trevor A Mori BSc (Hons), MRACI CChem, PhD (Distinction), Beth P Hands BEd, BSocWk, MEd, PhD and Leon A Adams MBBS, FRACP, PhD

Am J Gastroenterol 108: 778-785; advance online publication, April 2, 2013; doi:10.1038/ajg.2013.95

Subject Category: Liver

Functional GI Disorders

A Combined Nutrient and Lactulose Challenge Test Allows Symptom-Based Clustering of Patients With Irritable Bowel Syndrome

B Le Nevé PhD, I Posserud MD, L Böhn PhD, D Guyonnet PhD, P Rondeau PhD, K Tillisch MD, B Naliboff PhD, E A Mayer MD and M Simrén MD

Am J Gastroenterol 108: 786-795; advance online publication, April 16, 2013; doi:10.1038/ajg.2013.75

Subject Category: Functional GI Disorders

Association of Low Dietary Intake of Fiber and Liquids With Constipation: Evidence From the National Health and Nutrition Examination Survey

Alayne D Markland DO, MSc, Olafur Palsson PsyD, Patricia S Goode MSN, MD, Kathryn L Burgio PhD, Jan Busby-Whitehead MD and William E Whitehead PhD

Am J Gastroenterol 108: 796-803; advance online publication, April 9, 2013; doi:10.1038/ajg.2013.73

Subject Category: Functional GI Disorders

Colon/Small Bowel

Elemental Diets May Reduce the Risk of Aspiration Pneumonia in Bedridden Gastrostomy-Fed Patients Open

Akira Horiuchi MD, Yoshiko Nakayama MD, Ryosei Sakai PhD, Manabu Suzuki PhD, Masashi Kajiyama MD and Naoki Tanaka MD

Am J Gastroenterol 108: 804-810; advance online publication, February 12, 2013; doi:10.1038/ajg.2013.10

Subject Category: Colon/Small Bowel

A Randomized Controlled Trial of an Online Intervention to Improve Gluten-Free Diet Adherence in Celiac Disease

Kirby Sainsbury BA/BEd, DCP (candidate), Barbara Mullan PhD and Louise Sharpe PhD

Am J Gastroenterol 108: 811-817; advance online publication, March 5, 2013; doi:10.1038/ajg.2013.47

Subject Category: Colon/Small Bowel

Increasing Incidence of Celiac Disease in a North American Population

Jonas F Ludvigsson MD, PhD, Alberto Rubio-Tapia MD, Carol T van Dyke, L Joseph Melton III MD, Alan R Zinsmeister PhD, Brian D Lahr MS and Joseph A Murray MD

Am J Gastroenterol 108: 818-824; advance online publication, March 19, 2013; doi:10.1038/ajg.2013.60

Subject Category: Colon/Small Bowel

Oligo-Antigenic Diet in the Treatment of Chronic Anal Fissures. Evidence for a Relationship Between Food Hypersensitivity and Anal Fissures

Antonio Carroccio MD, Pasquale Mansueto MD, Giuditta Morfino MD, Alberto D'Alcamo MD, Valentina Di Paola MD, Giuseppe Iacono MD, Maurizio Soresi MD, Gregorio Scerrino MD, Emiliano Maresi MD, Gaspare Gulotta MD, GiovamBattista Rini MD and Sebastiano Bonventre MD

Am J Gastroenterol 108: 825-832; advance online publication, April 16, 2013; doi:10.1038/ajg.2013.58

Subject Category: Colon/Small Bowel

The Association of Serum Lipids With Colorectal Adenomas

Moon Hee Yang MD, Sanjay Rampal MD, MPH, Jidong Sung MD, Yoon-Ho Choi MD, Hee Jung Son MD, Jun Haeng Lee MD, Young Ho Kim MD, Dong Kyung Chang MD, Poong-Lyul Rhee MD, Jae J Kim MD, Jong Chul Rhee MD, Ho-Kyung Chun MD, Eliseo Guallar MD, DrPH and Juhee Cho PhD

Am J Gastroenterol 108: 833-841; advance online publication, April 2, 2013; doi:10.1038/ajg.2013.64

Subject Category: Colon/Small Bowel

Mucosal Cytokine Response After Short-Term Gluten Challenge in Celiac Disease and Non-Celiac Gluten Sensitivity

Margit Brottveit MD, PhD, Ann-Christin R Beitnes MD, PhD, Stig Tollefsen MSc, PhD, Jorunn E Bratlie BLS, Frode L Jahnsen MD, PhD, Finn-Eirik Johansen MSc, PhD, Ludvig M Sollid MD, PhD and Knut E A Lundin MD, PhD

Am J Gastroenterol 108: 842-850; advance online publication, April 16, 2013; doi:10.1038/ajg.2013.91

Subject Category: Colon/Small Bowel

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Letters to the Editor

An Altered Gut Microbiome Profile in a Child Affected by Crohn's Disease Normalized After Nutritional Therapy Open

Valeria D'Argenio MD, Vincenza Precone PhD, Giorgio Casaburi MS, Erasmo Miele MD, Massimo Martinelli MD, Annamaria Staiano MD, PhD, Francesco Salvatore MD, PhD and Lucia Sacchetti PhD

Am J Gastroenterol 108: 851-852; doi:10.1038/ajg.2013.46

Variable Use of Sedation During Colonoscopy and Impact on Outcome

I Shaikh MBBS, MS, MRCS, MD, FRCS, N Iqbal MBBS, MRCS, A Khan MBBS and S Doughan FRCS

Am J Gastroenterol 108: 853; doi:10.1038/ajg.2013.33

See also: Letter to the Editor by Ferlitsch et al.

Response to Shaikh et al.

Monika Ferlitsch MD, Christina Bannert MD and Arnulf Ferlitsch MD

Am J Gastroenterol 108: 853-854; doi:10.1038/ajg.2013.35

See also: Letter to the Editor by Shaikh et al.

An Electrocardiograph Should be Examined in Patients With a Hypersensitive Esophagus Before a Trial of Citalopram

Tae Hee Lee MD and Joon Seong Lee MD

Am J Gastroenterol 108: 854; doi:10.1038/ajg.2013.25

When Cure Becomes Worse Than the Disease

Amnon Sonnenberg MD, MSc and Charles R Boardman DNP, MS

Am J Gastroenterol 108: 854-855; doi:10.1038/ajg.2013.18

Successful Use of Thalidomide for Refractory Esophageal Crohn's Disease

Jodie A Barkin MD, Wayne B Schonfeld MD and Amar R Deshpande MD

Am J Gastroenterol 108: 855-857; doi:10.1038/ajg.2013.49

Successful Use of Infliximab in the Treatment of Corticosteroid Dependent Collagenous Colitis

Suresh Pola MD, Marianne Fahmy MD, Elisabeth Evans NP, Ann Tipps MD and William J Sandborn MD

Am J Gastroenterol 108: 857-858; doi:10.1038/ajg.2013.43

Fosfomycin-Containing Second-Line Treatment For Helicobacter pylori Infection

Josué Barahona-Garrido MD, Nery F Quiñonez MD, Eduardo Cerda-Contreras MD, PhD, Helga Maria Sarti MD and Félix I Téllez-Ávila MD, PhD

Am J Gastroenterol 108: 858-859; doi:10.1038/ajg.2013.48

Disease-Modifying Anti-Inflammatory Bowel Disease Drugs (DMAIDs): The Missing Term in the Literature

Laurent Peyrin-Biroulet MD, PhD

Am J Gastroenterol 108: 859-860; doi:10.1038/ajg.2013.53

Segmented Filamentous Bacteria-Like Organisms in Histological Slides of Ileo-Cecal Valves in Patients with Ulcerative Colitis

Michele Caselli MD, Dalila Tosini, Roberta Gafà MD, Antonio Gasbarrini MD and Giovanni Lanza MD

Am J Gastroenterol 108: 860-861; doi:10.1038/ajg.2013.61

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Announcements

Calendar of Courses, Symposiums and Conferences

Am J Gastroenterol 108: 862; doi:10.1038/ajg.2013.123