TABLE OF CONTENTS

Volume 107, Issue 1 (January 2012)

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The Red Section

ACG Presidential Introduction

Lawrence R Schiller MD, FACG

Am J Gastroenterol 107: 4; doi:10.1038/ajg.2011.433

Measuring Up: The ACG Today

Delbert L Chumley MD, FACG

Am J Gastroenterol 107: 5-7; doi:10.1038/ajg.2011.422

Mechanisms of Reflux Perception in Gastroesophageal Reflux Disease: A Review

Albert J Bredenoord MD

Am J Gastroenterol 107: 8-15; doi:10.1038/ajg.2011.286

Images of the Month

Am J Gastroenterol 107: 16; doi:10.1038/ajg.2011.435

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Clinical and Systematic Reviews

Review

Continuing Medical Education: January 2012

Am J Gastroenterol 107: 17; doi:10.1038/ajg.2011.446

Subject Category: Clinical and Systematic Review

Continuing Medical Education Chronic Constipation in the Elderly

Juan F Gallegos-Orozco MD, Amy E Foxx-Orenstein DO, Susan M Sterler RN and Jean M Stoa RN

Am J Gastroenterol 107: 18-25; doi:10.1038/ajg.2011.349

Subject Category: Clinical and Systematic Review

Continuing Medical Education Questions: January 2012

Abdullah Shatnawei MD, David Reed MD, Floyd Carter MD and Majd AlSayb MD

Am J Gastroenterol 107: 26; doi:10.1038/ajg.2011.447

Subject Category: Clinical and Systematic Review

Continuing Medical Education: January 2012

Am J Gastroenterol 107: 27; doi:10.1038/ajg.2011.440

Subject Category: Clinical and Systematic Review

Continuing Medical Education The Efficacy and Safety of Rifaximin for the Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis

Stacy B Menees MD, MSCRDSA, Monthira Maneerattannaporn MD, MSCRDSA, Hyungjin Myra Kim ScD and William D Chey MD, AGAF, FACG, FACP

Am J Gastroenterol 107: 28-35; doi:10.1038/ajg.2011.355

Subject Category: Clinical and Systematic Review

Continuing Medical Education Questions: January 2012

Kenneth R DeVault MD, FACG, Emily Carey DO, Ibrahim Hanouneh MD, Saul Kane MD and Udayakumar Navaneethan MD

Am J Gastroenterol 107: 36; doi:10.1038/ajg.2011.445

Subject Category: Clinical and Systematic Review

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Original Contributions

Esophagus

Phenotypes and Clinical Context of Hypercontractility in High-Resolution Esophageal Pressure Topography (EPT)

Sabine Roman MD, PhD, John E Pandolfino MD, Joan Chen MD, Lubomyr Boris, Daniel Luger and Peter J Kahrilas MD

Am J Gastroenterol 107: 37-45; doi:10.1038/ajg.2011.313

Subject Category: Esophagus

Liver

Risk of Hepatocellular Carcinoma in Diabetic Patients and Risk Reduction Associated With Anti-Diabetic Therapy: A Population-Based Cohort Study

Shih-Wei Lai MD, Pei-Chun Chen PhD, MSPH, Kuan-Fu Liao MD, MS, Chih-Hsin Muo MS, Cheng-Chieh Lin MD, PhD and Fung-Chang Sung PhD, MPH

Am J Gastroenterol 107: 46-52; doi:10.1038/ajg.2011.384

See also: Original Contribution by Baffy et al.

Subject Category: Liver

Editorial: Hepatocellular Carcinoma in Type 2 Diabetes: More Than Meets the Eye

György Baffy MD, PhD

Am J Gastroenterol 107: 53-55; doi:10.1038/ajg.2011.390

See also: Original Contribution by Lai et al.

Subject Category: Liver

The Spectrum of Sclerosing Cholangitis and the Relevance of IgG4 Elevations in Routine Practice

Khalid Alswat MD, MRCP, FACP, Nadya Al-Harthy MD, Waseem Mazrani FRCR, Ghazi Alshumrani MD, FRCR, Kartik Jhaveri MD and Gideon M Hirschfield MB, BChir, MRCP, PhD

Am J Gastroenterol 107: 56-63; doi:10.1038/ajg.2011.375

Subject Category: Liver

Frequency of Elevated Hepatocellular Carcinoma (HCC) Biomarkers in Patients With Advanced Hepatitis C

Richard K Sterling MD, MSc, Elizabeth C Wright PhD, Timothy R Morgan MD, Leonard B Seeff MD, John C Hoefs MD, Adrian M Di Bisceglie MD, Jules L Dienstag MD and Anna S Lok MD and the HALT-C Trial Group

Am J Gastroenterol 107: 64-74; doi:10.1038/ajg.2011.312

Subject Category: Liver

Functional GI Disorders

Combination of Allergic Factors Can Worsen Diarrheic Irritable Bowel Syndrome: Role of Barrier Defects and Mast Cells

M Vivinus-Nébot MD, R Dainese MD, R Anty MD, PhD, M C Saint-Paul MD, J L Nano PhD, N Gonthier, S Marjoux MD, G Frin-Mathy MD, G Bernard PhD, X Hébuterne MD, PhD, A Tran MD, PhD, V Theodorou PhD and T Piche MD, PhD

Am J Gastroenterol 107: 75-81; doi:10.1038/ajg.2011.315

Subject Category: Functional GI Disorders

Risk of Gastroparesis in Subjects With Type 1 and 2 Diabetes in the General Population

Rok Seon Choung MD, G Richard Locke III MD, Cathy D Schleck BS, Alan R Zinsmeister PhD, L Joseph Melton III MD and Nicholas J Talley MD, PhD

Am J Gastroenterol 107: 82-88; doi:10.1038/ajg.2011.310

Subject Category: Functional GI Disorders

Colon/Small Bowel

The Epidemiology of Community-Acquired Clostridium difficile Infection: A Population-Based Study

Sahil Khanna MBBS, Darrell S Pardi MD, MS, FACG, Scott L Aronson MD, Patricia P Kammer CCRP, Robert Orenstein DO, Jennifer L St Sauver PhD, W Scott Harmsen MS and Alan R Zinsmeister PhD

Am J Gastroenterol 107: 89-95; doi:10.1038/ajg.2011.398

See also: Original Contribution by Leffler et al.

Subject Category: Colon/Small Bowel

Editorial: Not So Nosocomial Anymore: The Growing Threat of Community-Acquired Clostridium difficile

Daniel A Leffler MS, MD and J Thomas Lamont MD

Am J Gastroenterol 107: 96-98; doi:10.1038/ajg.2011.404

See also: Original Contribution by Khanna et al.

Subject Category: Colon/Small Bowel

Are Fecal Immunochemical Test Characteristics Influenced by Sample Return Time? A Population-Based Colorectal Cancer Screening Trial

Aafke HC van Roon MD, Lieke Hol MD, PhD, Anneke J van Vuuren PhD, Jan Francke, Martine Ouwendijk, Angela Heijens, Nicole Nagtzaam, Jacqueline CIY Reijerink MSc, Alexandra CM van der Togt, Marjolein van Ballegooijen MD, PhD, Ernst J Kuipers MD, PhD and Monique E van Leerdam MD, PhD

Am J Gastroenterol 107: 99-107; doi:10.1038/ajg.2011.396

See also: Original Contribution by Levin et al.

Subject Category: Colon/Small Bowel

Editorial: Taking FIT to the People: Out of the Office and Into the Mail

Theodore R Levin MD

Am J Gastroenterol 107: 108-110; doi:10.1038/ajg.2011.401

See also: Original Contribution by van Roon et al.

Subject Category: Colon/Small Bowel

In Vitro Gliadin Challenge: Diagnostic Accuracy and Utility for the Difficult Diagnosis of Celiac Disease

Raffaella Tortora MD, Ilaria Russo PhD, Giovanni D De Palma MD, Alessandro Luciani PhD, Antonio Rispo MD, Fabiana Zingone MD, Paola Iovino MD, Pietro Capone MD and Carolina Ciacci MD

Am J Gastroenterol 107: 111-117; doi:10.1038/ajg.2011.311

Subject Category: Colon/Small Bowel

Pancreas and Biliary Tract

Clinicopathologic Features of Intraductal Papillary Neoplasm of the Bile Duct According to Histologic Subtype

Kwang Min Kim MD, Jong Kyun Lee MD, PhD, Jae Uk Shin MD, Kwang Hyuck Lee MD, PhD, Kyu Taek Lee MD, PhD, Ji-Youn Sung MD, Kee-Taek Jang MD, PhD, Jin Seok Heo MD, PhD, Seong-Ho Choi MD, PhD, Dong Wook Choi MD, PhD and Jae Hoon Lim MD, PhD

Am J Gastroenterol 107: 118-125; doi:10.1038/ajg.2011.316

Subject Category: Pancreas/Biliary Tract

Expression and Clinicopathological Significance of Notch Signaling and Cell-Fate Genes in Biliary Tract Cancer

Pawel K Mazur PhD, Marc-Oliver Riener MD, Wolfram Jochum MD, Glen Kristiansen MD, Achim Weber MD, Roland M Schmid MD and Jens T Siveke MD

Am J Gastroenterol 107: 126-135; doi:10.1038/ajg.2011.305

Subject Category: Pancreas/Biliary Tract

Pediatrics

Hepatitis B Immunity and Response to Booster Vaccination in Children With Inflammatory Bowel Disease Treated With Infliximab

Jonathan Moses MD, Naim Alkhouri MD, Angela Shannon MD, Kathy Raig RN, Rocio Lopez MS, Lara Danziger-Isakov MD, Ariel E Feldstein MD, Nizar N Zein MD, Robert Wyllie MD and Christine Carter-Kent MD

Am J Gastroenterol 107: 133-138; doi:10.1038/ajg.2011.295

Subject Category: Pediatrics

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Letters to the Editor

Re: Screening Colonoscopy for the Underserved

Joseph C Yarze MD, FACP, FACG, FASGE, AGAF and John Rugge MD

This letter underwent AJG editorial review.

Am J Gastroenterol 107: 139; doi:10.1038/ajg.2011.331

See also: Letter to the Editor by DiMase et al.

Response to Yarze and Rugge

Joseph D DiMase MD, FACG, FACP

This letter underwent AJG editorial review.

Am J Gastroenterol 107: 139; doi:10.1038/ajg.2011.332

See also: Letter to the Editor by Yarze et al.

Altered Bile Acid Pool Using IBAT Inhibitors for Constipation: A Potentially Increased Risk of Malignancy

Palak Jitendrakumar Trivedi BSc (Hons), MBBS, MRCP (UK) and Stephen Ward BSc (Hons), MBBS, MRCS (Eng)

This letter underwent AJG editorial review.

Am J Gastroenterol 107: 140; doi:10.1038/ajg.2011.378

See also: Letter to the Editor by Chey et al.

Response to Drs Trivedi and Ward

William D Chey MD, FACG, Michael Camilleri MD, Lin Chang MD, Leif Rikner MD and Hans Graffner MD

This letter underwent AJG editorial review.

Am J Gastroenterol 107: 140-141; doi:10.1038/ajg.2011.379

See also: Letter to the Editor by Trivedi et al.

Vaccinations While On Thiopurines: Some Protection Is Better Than None

Gil Y Melmed MD, MS

Am J Gastroenterol 107: 141-142; doi:10.1038/ajg.2011.320

Chronic Right Lower Abdominal Pain Due to Lumbar Ossification of the Posterior Longitudinal Ligament Open

Toshikatsu Okumura MD, Kazuhito Ebisawa MD, Masumi Ohhira MD, Tsukasa Nozu MD, Yoshihiro Tsuchiya MD, Mitsutaka Inoue MD and Masahito Tanaka MD

Am J Gastroenterol 107: 142-143; doi:10.1038/ajg.2011.319

Change in Malpractice Claims in Japanese Gastroenterological Practice

Toru Hiyama MD, PhD, Masaharu Yoshihara MD, PhD, Shinji Tanaka MD, PhD and Kazuaki Chayama MD, PhD

This letter underwent AJG editorial review.

Am J Gastroenterol 107: 143-144; doi:10.1038/ajg.2011.321

Advanced-Stage Syphilis Unmasking After Immunomodulator Therapy in a Patient With Ulcerative Colitis

Dominik Bettenworth MD, Martin Floer MD, Thomas Krummenerl MD, Wolfgang Wehrmann MD, Leo Schärer MD and Jan Heidemann MD

This letter was reviewed externally.

Am J Gastroenterol 107: 144-145; doi:10.1038/ajg.2011.330

Helicobacter pylori vacA Intermediate Region Genotyping and Progression of Gastric Preneoplastic Lesions

Rui M Ferreira BSc, Ceu Figueiredo PhD, Catalina Bonet Lic, Maria L Pardo PhD, Juan M Ruiz Liso PhD, Pablo Alonso PhD, Nuria Sala PhD, Gabriel Capella PhD, Jose M Sanz-Anquela PhD and Carlos A González PhD

Am J Gastroenterol 107: 145-146; doi:10.1038/ajg.2011.389

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Announcements

Calendar of Courses, Symposiums, and Conferences

Am J Gastroenterol 107: 147; doi:10.1038/ajg.2011.441

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Errata, Corrigenda and Retractions

Erratum: Abstracts Submitted for the 76th Annual Scientific Meeting of the American College of Gastroenterology FREE

Am J Gastroenterol 107: 148-149; doi:10.1038/ajg.2011.442

Corrigendum: The Epidemiology of Community-Acquired Clostridium difficile Infection: A Population-Based Study FREE

Sahil Khanna, Darrell S Pardi, Scott L Aronson, Patricia P Kammer, Robert Orenstein, Jennifer L St Sauver, W Scott Harmsen and Alan R Zinsmeister

Am J Gastroenterol 107: 150; doi:10.1038/ajg.2011.444