TABLE OF CONTENTS

Volume 104, Issue 7 (July 2009)

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The Red Section

Reflections on Medical Practice

Physicians and Health-Care Reform: Rolling Up Our Sleeves or Rolling the Dice? FREE

Michael Kirsch MD

Am J Gastroenterol 104: 1617-1619; doi:10.1038/ajg.2009.340

The Expert's Corner

Misdiagnosis of Autoimmune Pancreatitis: A Caution to Clinicians FREE

Timothy B Gardner MD, Michael J Levy MD, Naoki Takahashi MD, Thomas C Smyrk MD and Suresh T Chari MD

Am J Gastroenterol 104: 1620-1623; doi:10.1038/ajg.2008.89

Methodology

Statistical Graphics in AJG: Save the Ink for the Information FREE

Jason T Connor PhD, FACG

Am J Gastroenterol 104: 1624-1630; doi:10.1038/ajg.2009.259

A Look Back

Eder-Puestow "Stringless" Dilators FREE

Robert E Kravetz MD, MACG

Am J Gastroenterol 104: 1631-1632; doi:10.1038/ajg.2009.273

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Original Contributions

Stomach

Time Trends and Impact of Upper and Lower Gastrointestinal Bleeding and Perforation in Clinical Practice

Angel Lanas MD, DSc, Luis A García-Rodríguez MD, Mónica Polo-Tomás MSc, Marta Ponce MD, Inmaculada Alonso-Abreu MD, Maria Angeles Perez-Aisa MD, DSc, Javier Perez-Gisbert MD, DSc, Luis Bujanda MD, DSc, Manuel Castro MD, DSc, Maria Muñoz MD, Luis Rodrigo MD, DSc, Xavier Calvet MD, DSc, Dolores Del-Pino MD and Santiago Garcia MD

Am J Gastroenterol 104: 1633-1641; advance online publication, May 5, 2009; doi:10.1038/ajg.2009.164

Subject Category: Stomach

H. pylori Eradication Prevents the Progression of Gastric Intestinal Metaplasia in Reflux Esophagitis Patients Using Long-Term Esomeprazole

Hsiao-Bai Yang MD, Bor-Shyang Sheu MD, Shin-Tar Wang PhD, Hsiu-Chi Cheng MD, Wei-Lun Chang MD and Wei-Ying Chen MD

Am J Gastroenterol 104: 1642-1649; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.172

Subject Category: Stomach

Endoscopy

Low-Dose Propofol Sedation for Diagnostic Esophagogastroduodenoscopy: Results in 10,662 Adults

Akira Horiuchi MD, Yoshiko Nakayama MD, Nao Hidaka MD, Yasuyuki Ichise MD, Masashi Kajiyama MD and Naoki Tanaka MD

Am J Gastroenterol 104: 1650-1655; advance online publication, June 9, 2009; doi:10.1038/ajg.2009.250

Subject Category: Endoscopy

Editorial: Doc, Can I Drive Home? FREE

John J Vargo MD, MPH, FACG

Am J Gastroenterol 104: 1656-1657; doi:10.1038/ajg.2009.262

Subject Category: Endoscopy

Continuing Medical Education: July 2009

Am J Gastroenterol 104: 1658; doi:10.1038/ajg.2009.358

Subject Category: Endoscopy

Continuing Medical Education Adenomas Are Detected More Often in Morning Than in Afternoon Colonoscopy

Madhusudhan R Sanaka MD, Fnu Deepinder MD, Prashanthi N Thota MD, Rocio Lopez MS and Carol A Burke MD

Am J Gastroenterol 104: 1659-1664; advance online publication, June 2, 2009; doi:10.1038/ajg.2009.249

Subject Category: Endoscopy

Continuing Medical Education Questions: July 2009

James S Scolapio MD, Anna M Buchner MD, Kanwar R S Gill MD and Muhammad Hasan MD

Am J Gastroenterol 104: 1665; doi:10.1038/ajg.2009.359

Subject Category: Endoscopy

Editorial: The Influence of Timing of Colonoscopy on Adenoma Detection: Is Timing Everything? FREE

Joseph Vicari MD

Am J Gastroenterol 104: 1666-1667; doi:10.1038/ajg.2009.258

Subject Category: Endoscopy

Disparities in Emergency Department Wait Times for Acute Gastrointestinal Illnesses: Results From the National Hospital Ambulatory Medical Care Survey, 1997–2006

Bechien U Wu MD, MPH, Peter A Banks MD and Darwin L Conwell MD, MS

Am J Gastroenterol 104: 1668-1673; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.189

Subject Category: Endoscopy

A Randomized Controlled Clinical Trial of Palliative Therapies for Patients With Inoperable Esophageal Cancer

Jonathan Shenfine MBBS, FRCS, PhD, Paul McNamee MSc, PhD, Nick Steen MSc, BSc, PhD, John Bond BA (Hons.) and S Michael Griffin MBBS, FRCS (Eng.), FRCS (Ed.), MD

Am J Gastroenterol 104: 1674-1685; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.155

Subject Category: Endoscopy

Liver and Biliary Tract

Response to Therapy With Pegylated Interferon and Ribavirin for Chronic Hepatitis C in Hispanics Compared to Non-Hispanic Whites

Stanley Yu MD, Jeffrey M Douglass MD, Clifford Qualls PhD, Sanjeev Arora MD and Jeffrey C Dunkelberg MD, PhD

Am J Gastroenterol 104: 1686-1692; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.173

Subject Category: Liver and Biliary Tract

Incidence and Risk Factors of Progression to Cirrhosis in Inactive Carriers of Hepatitis B Virus

Chia-Ming Chu MD and Yun-Fan Liaw MD

Am J Gastroenterol 104: 1693-1699; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.187

Subject Category: Liver and Biliary Tract

A Shorter Duration of Pre-Transplant Abstinence Predicts Problem Drinking After Liver Transplantation

Puneeta Tandon MD, FRCP(C), MSc(Epi), Karen J Goodman PhD, Mang M Ma MD, FRCP(C), Winnie W Wong BSc, MD, FRCP(C), MSc(Epi), Andrew L Mason MBBS, MRCP, Glenda Meeberg RN, BScN, MN, Donna Bergsten RN, Michelle Carbonneau RN, BScN, MN and Vincent G Bain MD, FRCP(C)

Am J Gastroenterol 104: 1700-1706; advance online publication, May 26, 2009; doi:10.1038/ajg.2009.226

Subject Category: Liver and Biliary Tract

Idiopathic Portal Hypertension in Patients With HIV Infection Treated With Highly Active Antiretroviral Therapy

Pik-Eu Chang MBBS, MRCP(UK), Rosa Miquel MD, Jose-Luis Blanco MD, Montserrat Laguno MD, Miguel Bruguera MD, Juan-G Abraldes MD, Jaime Bosch MD and Juan-Carlos Garcia-Pagan MD

Am J Gastroenterol 104: 1707-1714; advance online publication, May 26, 2009; doi:10.1038/ajg.2009.165

Subject Category: Liver and Biliary Tract

Serum Alanine Aminotransferase, Metabolic Syndrome, and Cardiovascular Disease in an Australian Population

John K Olynyk BMedSc, MBBS, FRACP, MD, Matthew W Knuiman BSc, PhD, Mark L Divitini BSc, Timothy M E Davis MBBS, FRACP, PhD, John Beilby BSc, PhD and Joseph Hung MBBS, FRACP

Am J Gastroenterol 104: 1715-1722; advance online publication, June 2, 2009; doi:10.1038/ajg.2009.229

Subject Category: Liver and Biliary Tract

Inflammatory Bowel Disease

Epistasis Between Toll-Like Receptor-9 Polymorphisms and Variants in NOD2 and IL23R Modulates Susceptibility to Crohn's Disease

Helga P Török MD, Jürgen Glas MD, Ilona Endres, Laurian Tonenchi MD, Molla Y Teshome MD, Martin Wetzke, Wolfram Klein MD, Peter Lohse MD, Thomas Ochsenkühn MD, Matthias Folwaczny DMD, Burkhard Göke MD, Christian Folwaczny MD, Bertram Müller-Myhsok MD and Stephan Brand MD

Am J Gastroenterol 104: 1723-1733; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.184

Subject Category: Inflammatory Bowel Disease

Editorial: Gene–Gene Interactions in Inflammatory Bowel Disease: Biological and Clinical Implications FREE

Jean-Paul Achkar MD, FACG and Claudio Fiocchi MD

Am J Gastroenterol 104: 1734-1736; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.179

Subject Category: Inflammatory Bowel Disease

Novel Genetic Risk Markers for Ulcerative Colitis in the IL2/IL21 Region Are in Epistasis With IL23R and Suggest a Common Genetic Background for Ulcerative Colitis and Celiac Disease

Jürgen Glas MD, Johannes Stallhofer, Stephan Ripke MD, Martin Wetzke MD, Simone Pfennig, Wolfram Klein MD, Jörg T Epplen MD, Thomas Griga MD, Uwe Schiemann MD, Martin Lacher MD, Sibylle Koletzko MD, Matthias Folwaczny DMD, Peter Lohse MD, Burkhard Göke MD, Thomas Ochsenkühn MD, Bertram Müller-Myhsok MD and Stephan Brand MD

Am J Gastroenterol 104: 1737-1744; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.163

Subject Category: Inflammatory Bowel Disease

Candida albicans Colonization and ASCA in Familial Crohn's Disease

Annie Standaert-Vitse PhD, Boualem Sendid PhD, Marie Joossens MSc, Nadine François BSc, Peggy Vandewalle-El Khoury MSc, Julien Branche MD, Herbert Van Kruiningen MD, Thierry Jouault PhD, Paul Rutgeerts MD, Corinne Gower-Rousseau MD, Christian Libersa MD, Christel Neut PhD, Franck Broly, Mathias Chamaillard PhD, Séverine Vermeire MD, Daniel Poulain PhD and Jean-Frédéric Colombel MD

Am J Gastroenterol 104: 1745-1753; advance online publication, May 26, 2009; doi:10.1038/ajg.2009.225

Subject Category: Inflammatory Bowel Disease

The Manitoba IBD Index: Evidence for a New and Simple Indicator of IBD Activity

Ian Clara PhD, Lisa M Lix PhD, John R Walker PhD, Lesley A Graff PhD, Norine Miller RN, Linda Rogala RN, Patricia Rawsthorne RN and Charles N Bernstein MD

Am J Gastroenterol 104: 1754-1763; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.197

Subject Category: Inflammatory Bowel Disease

Functional GI Disorders

Does the Presence of a Hiatal Hernia Affect the Efficacy of the Reflux Inhibitor Baclofen During Add-On Therapy?

Hanneke Beaumont MD, PhD and Guy E E Boeckxstaens MD, PhD

Am J Gastroenterol 104: 1764-1771; advance online publication, June 2, 2009; doi:10.1038/ajg.2009.247

Subject Category: Functional GI Disorders

Psychosocial Distress and Somatic Symptoms in Community Subjects With Irritable Bowel Syndrome: A Psychological Component Is the Rule

Rok Seon Choung MD, G Richard Locke III MD, Alan R Zinsmeister PhD, Cathy D Schleck BS and Nicholas J Talley MD, PhD

Am J Gastroenterol 104: 1772-1779; advance online publication, June 2, 2009; doi:10.1038/ajg.2009.239

Subject Category: Functional GI Disorders

Pancreas

Pancreatic Ductal Abnormalities Documented by Secretin-Enhanced MRCP in Asymptomatic Subjects With Chronic Pancreatic Hyperenzymemia

Pier Alberto Testoni MD, A Mariani MD, S Curioni MD, A Giussani MD and E Masci MD

Am J Gastroenterol 104: 1780-1786; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.158

Subject Category: Pancreas

Editorial: Secretin-Enhanced MRCP: Proceed With Cautious Optimism FREE

Nisha I Sainani MD and Darwin L Conwell MD

Am J Gastroenterol 104: 1787-1789; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.168

Subject Category: Pancreas

Pathology

High Prevalence of Fatty Acid Synthase Expression in Colorectal Cancers in Middle Eastern Patients and Its Potential Role as a Therapeutic Target

Shahab Uddin PhD, Azhar R Hussain MBBS, Maqbool Ahmed PhD, Jehad Abubaker PhD, Nasser Al-Sanea MD, Alaa AbdulJabbar MD, Luai H Ashari MD, Samar Alhomoud MD, Fouad Al-Dayel MD, Prashant Bavi MD and Khawla S Al-Kuraya MD, FCAP

Am J Gastroenterol 104: 1790-1801; advance online publication, June 2, 2009; doi:10.1038/ajg.2009.230

Subject Category: Pathology

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Clinical Reviews

Review

Management and Treatment of Patients With Cirrhosis and Portal Hypertension: Recommendations From the Department of Veterans Affairs Hepatitis C Resource Center Program and the National Hepatitis C Program FREE

Guadalupe Garcia-Tsao MD and Joseph Lim MD and Members of the Veterans Affairs Hepatitis C Resource Center Program

Am J Gastroenterol 104: 1802-1829; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.191

Continuing Medical Education: July 2009

Am J Gastroenterol 104: 1830; doi:10.1038/ajg.2009.350

Continuing Medical Education Efficacy of 5-HT3 Antagonists and 5-HT4 Agonists in Irritable Bowel Syndrome: Systematic Review and Meta-Analysis

Alexander C Ford MD, MRCP, Lawrence J Brandt MD, MACG, Christine Young BHSc, William D Chey MD, FACG, Amy E Foxx-Orenstein DO, FACG and Paul Moayyedi PhD, FRCP

Am J Gastroenterol 104: 1831-1843; advance online publication, May 26, 2009; doi:10.1038/ajg.2009.223

Continuing Medical Education Questions: July 2009

James S Scolapio MD, Karen C Kim MD, Ying Hong Wang MD, Ashish Atreja MD and Dian Chiang MD

Am J Gastroenterol 104: 1844; doi:10.1038/ajg.2009.357

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Letters to the Editor

Liver Diseases and Venous Thromboembolism

Amer A Alkhatib MD

Am J Gastroenterol 104: 1845; doi:10.1038/ajg.2009.234

Response to Alkhatib

K K Søgaard MD

Am J Gastroenterol 104: 1845-1846; doi:10.1038/ajg.2009.236

Colonic Perforation After Colonoscopy in Patients With Collagenous Colitis

L Cuoco MD, PhD, V Bertoncello MD and Mario Salvagnini MD, PhD

Am J Gastroenterol 104: 1846-1847; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.178

Response to Cuoco

Daniela S Allende MD, Mary P Bronner MD and Shari L Taylor MD

Am J Gastroenterol 104: 1847; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.182

Duodenal Intraepithelial Lymphocytosis: Celiac Disease or Not?

Pekka Collin MD, PhD, Katri Kaukinen MD, PhD and Markku Mäki MD, PhD

Am J Gastroenterol 104: 1847; doi:10.1038/ajg.2009.206

Response to Collin et al.

Jennifer L Vande Voort MD and Joseph A Murray MD

Am J Gastroenterol 104: 1848; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.217

The Genetics of Alcoholic Liver Disease: Better Patient Group Definition Is Required

Eric Nguyen-Khac MD, PhD, Hakim Houchi MSc, Martine Daoust PhD and Mickaël Naassïla PhD

Am J Gastroenterol 104: 1848-1849; doi:10.1038/ajg.2009.255

Response to Nguyen-Khac et al.

Dermot Gleeson MD BSc FRCP

Am J Gastroenterol 104: 1849; doi:10.1038/ajg.2009.260

BIS: Hit or Miss?

Mohammed A Qadeer MD, MPH and John J Vargo MD, MPH

Am J Gastroenterol 104: 1850; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.207

Response to Qadeer and Vargo

Stefan von Delius MD and Wolfgang Huber MD

Am J Gastroenterol 104: 1850-1851; doi:10.1038/ajg.2009.211

NAFLD and Cardiovascular Risk: Direct Evidence for the Tale of Two Ages

Amedeo Lonardo MD and Paola Loria MD

Am J Gastroenterol 104: 1851-1852; doi:10.1038/ajg.2009.233

Portal Vein Tumor Thrombosis Revascularization During Sorafenib Treatment for Hepatocellular Carcinoma

Marialuisa Novi MD, Ernesto C Lauritano MD, Anna C Piscaglia MD, Brunella Barbaro MD, Maria A Zocco MD, PhD, Maurizio Pompili MD and Antonio Gasbarrini MD

Am J Gastroenterol 104: 1852-1854; advance online publication, May 5, 2009; doi:10.1038/ajg.2009.140

Distinguishing Between Anti-Neutrophil Cytoplasmic Antibody Patterns in Inflammatory Bowel Disease: Is the "Atypical Pattern" Adding More Information?

Josué Barahona-Garrido MD, Jorge Hernández-Calleros MD, Javier Cabiedes PhD, Helga M Sarti MD, Aldo Torre MD, Aldo J Montaño-Loza MD, and Jesús K Yamamoto-Furusho MD, PhD

Am J Gastroenterol 104: 1854-1855; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.144

Safety of Capsule Endoscopy in the Setting of Implanted Cardiac Defibrillators: A Brief Report

Georg Elias MD and Nabil Toubia MD

Am J Gastroenterol 104: 1856-1857; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.143

Topically Administered Infliximab Can Work in Ulcerative Proctitis Despite the Ineffectiveness of Intravenous Induction Therapy

Tamás Molnár MD, PhD, Klaudia Farkas MD, Ferenc Nagy MD, PhD, István Németh MD and Tibor Wittmann MD, PhD

Am J Gastroenterol 104: 1857-1858; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.147

Primary Herpes Simplex Type 1 Esophagitis Followed by Recurrent Perianal Herpetic Infection in an Immunocompetent Host

N K H de Boer MD, PhD, C van Krimpen MD, PhD and J P Kuyvenhoven MD, PhD

Am J Gastroenterol 104: 1858-1859; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.193

Medium- and Small-Vessel Vasculitis With Large Bowel Infarction in Systemic Lupus Erythematosus: A Case Report

Raafat Makary MD, PhD, Cindy Davis MD and Sania Shuja MD, PhD

Am J Gastroenterol 104: 1859-1860; doi:10.1038/ajg.2009.242

The First Reported Case of Nodular Lymphocyte–Predominant Hodgkin's Lymphoma of the Appendix

Douglas M Weine MD, Robert M Gelfand MD, Cory R Fraser MD and Arnold L Weg MD

Am J Gastroenterol 104: 1860-1861; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.185

Liver Injury From Diclofenac or Acetaminophen?

Weekitt Kittisupamongkol MD

Am J Gastroenterol 104: 1862; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.170

Melatonin Arrhythmia Is Corrected After Liver Transplantation

Juan Cordoba MD, Petra Steindl MD and Andres T Blei MD

Am J Gastroenterol 104: 1862-1863; advance online publication, May 19, 2009; doi:10.1038/ajg.2009.171

Duodenopancreatic Fistula Complicating Upper Gastrointestinal Crohn's Disease: Succesful Treatment With Infliximab

José A Pajares MD, Luis Hernández MD, Pedro Menchén MD, PhD and Luis Menchén MD, PhD

Am J Gastroenterol 104: 1863-1864; advance online publication, May 12, 2009; doi:10.1038/ajg.2009.180

"Comment on a Retraction": Author Response

Xavier Roblin MD, Laurent Peyrin-Biroulet MD, PhD, Jean-Marc Phélip MD, PhD, Stéphane Nancey MD, PhD and Bernard Flourié MD, PhD

Am J Gastroenterol 104: 1864-1865; doi:10.1038/ajg.2009.351

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Announcements

Calendar of Courses, Symposiums, and Conferences

Am J Gastroenterol 104: 1866; doi:10.1038/ajg.2009.338

GI Fellowship programs

Am J Gastroenterol 104: 1866-1893; doi:10.1038/ajg.2009.291

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Errata, Corrigenda and Retractions

Corrigendum: Effects of Adalimumab Maintenance Therapy on Health-Related Quality of Life of Patients With Crohn's Disease: Patient-Reported Outcomes of the CHARM Trial FREE

Edward V Loftus, Brian G Feagan, Jean-Frédéric Colombel, David T Rubin, Eric Q Wu, Andrew P Yu, Paul F Pollack, Jingdong Chao and Parvez Mulani

Am J Gastroenterol 104: 1894; doi:10.1038/ajg.2009.354

Erratum: Management and Treatment of Patients With Cirrhosis and Portal Hypertension: Recommendations From the Department of Veterans Affairs Hepatitis C Resource Center Program and the National Hepatitis C Program FREE

Guadalupe Garcia-Tsao and Joseph Lim and Members of the Veterans Affairs Hepatitis C Resource Center Program

Am J Gastroenterol 104: 1894; doi:10.1038/ajg.2009.360

Erratum: Characterization of Inflammatory Bowel Disease With Urinary Metabolic Profiling FREE

Horace R T Williams, I Jane Cox, David G Walker, Bernard V North, Venisha M Patel, Sara E Marshall, Derek P Jewell, Subrata Ghosh, Huw JW Thomas, Julian P Teare, Simon Jakobovits, Sebastian Zeki, Kenneth I Welsh, Simon D Taylor-Robinson and Timothy R Orchard

Am J Gastroenterol 104: 1894; doi:10.1038/ajg.2009.381

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