Case Report

The American Journal of Gastroenterology (2005) 100, 723–726; doi:10.1111/j.1572-0241.2005.41293.x

Pneumomediastinum Following Enteryx™ Injection for the Treatment of Gastroesophageal Reflux Disease

Kyung W Noh MD1, David S Loeb MD, FACP1, Andrew Stockland MD1 and Sami R Achem MD, FACP, FACG1

1Division of Gastroenterology and Hepatology; and Radiology Department, Mayo Clinic, Jacksonville, Florida

Correspondence: S. R. Achem, MD, FACP, FACG, Mayo Clinic, 2400 San Pablo Road, Jacksonville, FL 32224

Received 4 August 2004; Revised  0000; Accepted 2 November 2004.

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Abstract

We describe the case of a 68-year-old female who developed pneumomediastinum following the "Enteryx" procedure for the treatment of gastroesophageal reflux disease (GERD). The patient required hospitalization and parenteral antibiotics and responded favorably to a conservative approach. Similar complications have been observed with other endoscopic treatment modalities for GERD such as Stretta and suturing techniques. Our patient represents the third reported case of a serious complication after Enteryx implantation.

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