Featured
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Research Highlights |
A mammalian change of heart
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News |
Mutant stem cells can cause skin cancer at cuts
Cells meant to fix injuries can trigger tumours in cancer-prone mice.
- Erika Check Hayden
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Letter |
Circulating mitochondrial DAMPs cause inflammatory responses to injury
Severe trauma can lead to death and sepsis in the absence of apparent infection. Here evidence shows that mitochondrial debris, released from damaged cells, is present in the circulation of seriously injured trauma patients. Such debris is shown to activate neutrophils via specific formyl peptide receptors, triggering systemic inflammation and end organ injury.
- Qin Zhang
- , Mustafa Raoof
- & Carl J. Hauser
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News |
How the cell's powerhouses turn deadly
Mitochondria can trigger a lethal immune response after injuries.
- Heidi Ledford
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Research Highlights |
Neuroscience: Baby blues