Featured
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Article |
Rolling back human pluripotent stem cells to an eight-cell embryo-like stage
The development of a transgene-free, rapid and controllable method for producing eight-cell-like cells from human pluripotent stem cells provides a valuable resource to study early human embryogenesis.
- Md. Abdul Mazid
- , Carl Ward
- & Miguel A. Esteban
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Letter |
Establishment of mouse expanded potential stem cells
Cultures of expanded potential stem cells can be established from individual eight-cell blastomeres, and by direct conversion of mouse embryonic stem cells and induced pluripotent stem cells, highlighting the feasibility of establishing expanded potential stem cells for other mammalian species.
- Jian Yang
- , David J. Ryan
- & Pentao Liu
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Brief Communications Arising |
Failure to replicate the STAP cell phenomenon
- Alejandro De Los Angeles
- , Francesco Ferrari
- & George Q. Daley
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Review Article |
Hallmarks of pluripotency
In response to the need for a defined set of criteria to assess stem-cell potency, this review proposes guidelines for the evaluation of newly derived pluripotent stem cells, from functional assays to integrative molecular analyses of transcriptional, epigenetic and metabolic states.
- Alejandro De Los Angeles
- , Francesco Ferrari
- & George Q. Daley