Featured
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Letter |
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Therapy-resistant cancer cell states identified across diverse contexts are selectively vulnerable to ferroptotic cell death induced by inhibition of lipid peroxidase pathways converging on GPX4.
- Vasanthi S. Viswanathan
- , Matthew J. Ryan
- & Stuart L. Schreiber
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Letter |
Expression of tumour-specific antigens underlies cancer immunoediting
This paper illustrates that immunosurveillance and immunoediting can occur in an oncogene-driven endogenous tumour model provided that the tumours carry strong neoantigens not present in the host.
- Michel DuPage
- , Claire Mazumdar
- & Tyler Jacks
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Research Highlights |
Cancer genomics: Prognostic sign