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| Open AccessNanoscale flow cytometry reveals interpatient variability in HIV protease activity that correlates with viral infectivity and identifies drug-resistant viruses
- Michał M. Bonar
- , Caroline O. Tabler
- & John C. Tilton
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| Open AccessA novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation
- Cedric Joossen
- , Adrienn Baán
- & Paul Cos
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| Open AccessThe fatty-acid amide hydrolase inhibitor URB597 inhibits MICA/B shedding
- Kazuma Sekiba
- , Motoyuki Otsuka
- & Kazuhiko Koike
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| Open AccessPredominant synthesis of giant myofibrillar proteins in striated muscles of the long-tailed ground squirrel Urocitellus undulatus during interbout arousal
- Svetlana Popova
- , Anna Ulanova
- & Ivan Vikhlyantsev
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| Open AccessMatriptase processing of APLP1 ectodomain alters its homodimerization
- Erwan Lanchec
- , Antoine Désilets
- & Christine Lavoie
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| Open AccessTwo-Step Mechanism of Cyclin B Degradation Initiated by Proteolytic Cleavage with the 26 S Proteasome in Fish
- Toshinobu Tokumoto
- , Md. Forhad Hossain
- & Mika Tokumoto
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| Open AccessThe aryl hydrocarbon receptor pathway controls matrix metalloproteinase-1 and collagen levels in human orbital fibroblasts
- Elisa Roztocil
- , Christine L. Hammond
- & Collynn F. Woeller
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| Open AccessOsteogenic impact of pro-apoptotic caspase inhibitors in MC3T3-E1 cells
- Adéla Kratochvílová
- , Barbora Veselá
- & Eva Matalová
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| Open AccessMonitoring protease activity in biological tissues using antibody prodrugs as sensing probes
- Olga Vasiljeva
- , Elizabeth Menendez
- & W. Michael Kavanaugh
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| Open AccessInterspecies comparison of simultaneous thrombin and plasmin generation
- Ivan D. Tarandovskiy
- , Hye Kyung H. Shin
- & Paul W. Buehler
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| Open AccessGraphene quantum dots as cysteine protease nanocarriers against stored grain insect pests
- Muazzama Batool
- , Dilshad Hussain
- & Qamar Saeed
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| Open AccessThe Proteolytic Fraction From Vasconcellea cundinamarcensis Latex Displays Anti-Inflammatory Effect in A Mouse Model of Acute TNBS-Induced Colitis
- Ronniel Morais Albuquerque
- , Marina Passos Pizzitola
- & Miriam Teresa Paz Lopes
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| Open AccessThermostabilization of VPR, a kinetically stable cold adapted subtilase, via multiple proline substitutions into surface loops
- K. R. Óskarsson
- , A. F. Sævarsson
- & M. M. Kristjánsson
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| Open AccessSilencing of SENP2 in Multiple Myeloma Induces Bortezomib Resistance by Activating NF-κB Through the Modulation of IκBα Sumoylation
- Hongyi Xie
- , Yuanliang Gu
- & Peng Shu
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| Open AccessAn experiment-informed signal transduction model for the role of the Staphylococcus aureus MecR1 protein in β-lactam resistance
- Bruno S. Belluzo
- , Luciano A. Abriata
- & Leticia I. Llarrull
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| Open AccessCharacterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP)
- Nis V. Nielsen
- , Elfie Roedel
- & Sandip M. Kanse
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| Open AccessMolecular and structural insights into an asymmetric proteolytic complex (ClpP1P2) from Mycobacterium smegmatis
- Jyotsna Nagpal
- , Jason J. Paxman
- & David A. Dougan
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| Open AccessUbiquitin carboxyl-terminal hydrolases are required for period maintenance of the circadian clock at high temperature in Arabidopsis
- Ryosuke Hayama
- , Peizhen Yang
- & George Coupland
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| Open AccessAntimalarial Quinoline Drugs Inhibit β-Hematin and Increase Free Hemin Catalyzing Peroxidative Reactions and Inhibition of Cysteine Proteases
- Tomás Herraiz
- , Hugo Guillén
- & Vicente J. Arán
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| Open AccessThe C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases
- Tibisay Guevara
- , Hagen Körschgen
- & F. Xavier Gomis-Rüth
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| Open AccessMycoplasma hyopneumoniae surface-associated proteases cleave bradykinin, substance P, neurokinin A and neuropeptide Y
- Veronica Maria Jarocki
- , Benjamin Bernard Armando Raymond
- & Steven Philip Djordjevic
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| Open AccessAn Internally Quenched Fluorescent Peptide Substrate for Protealysin
- Maria A. Karaseva
- , Ksenia N. Chukhontseva
- & Ilya V. Demidyuk
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| Open AccessFragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase
- Yasumitsu Sakamoto
- , Yoshiyuki Suzuki
- & Nobutada Tanaka
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| Open AccessApplication of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease
- Bethany M. Anderson
- , Daniel P. Poole
- & Laura E. Edgington-Mitchell
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| Open AccessA common variant of the pregnancy-associated plasma protein-A (PAPPA) gene encodes a protein with reduced proteolytic activity towards IGF-binding proteins
- Jane Alrø Bøtkjær
- , Pernille Rimmer Noer
- & Claus Yding Andersen
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| Open AccessE40, a novel microbial protease efficiently detoxifying gluten proteins, for the dietary management of gluten intolerance
- Linda Cavaletti
- , Anna Taravella
- & Gianfranco Mamone
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| Open AccessA protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases
- Daisuke Nishimiya
- , Yoshirou Kawaguchi
- & Ryuji Hashimoto
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| Open AccessExosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis
- Salvatore Santamaria
- , Kazuhiro Yamamoto
- & Josefin Ahnström
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| Open AccessVps10-mediated targeting of Pep4 determines the activity of the vacuole in a substrate-dependent manner
- Fahd Boutouja
- , Christian M. Stiehm
- & Harald W. Platta
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| Open AccessPremedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation
- Salome R. T. Rehm
- , Natalia F. Smirnova
- & Dieter E. Jenne
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| Open AccessPurification and characterization of a novel, highly potent fibrinolytic enzyme from Bacillus subtilis DC27 screened from Douchi, a traditional Chinese fermented soybean food
- Yuanliang Hu
- , Dan Yu
- & Yongmei Hu
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| Open AccessSimultaneous assay for protease activities of hepatitis C virus and human immunodeficiency virus based on fluorescence detection
- Tsutomu Kabashima
- , Keiko Tonooka
- & Takayuki Shibata
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| Open AccessProbing prothrombin structure by limited proteolysis
- Laura Acquasaliente
- , Leslie A. Pelc
- & Enrico Di Cera
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| Open AccessIdentification of Allosteric Inhibitors against Active Caspase-6
- Agne Tubeleviciute-Aydin
- , Alexandre Beautrait
- & Andrea C. LeBlanc
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| Open AccessSequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis
- Akia N. Parks
- , Juhi Nahata
- & Manu O. Platt
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| Open AccessA complex of novel protease inhibitor, ovostatin homolog, with its cognate proteases in immature mice uterine luminal fluid
- Hsien-Lu Huang
- , Szu-Chin Li
- & Jin-Fong Wu
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| Open AccessDevelopment of a 13C Stable Isotope Assay for Dipeptidyl Peptidase-4 Enzyme Activity A New Breath Test for Dipeptidyl Peptidase Activity
- Roger Yazbeck
- , Simone Jaenisch
- & Ross N. Butler
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| Open AccessIdentification of fibrinogen as a natural inhibitor of MMP-2
- Hassan Sarker
- , Eugenio Hardy
- & Carlos Fernandez-Patron
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| Open AccessThe ubiquitin interacting motifs of USP37 act on the proximal Ub of a di-Ub chain to enhance catalytic efficiency
- Noah Manczyk
- , Gianluca Veggiani
- & Frank Sicheri
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| Open AccessTargeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice
- Jelle J. Posthuma
- , Jens J. N. Posma
- & Henri M. H. Spronk
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| Open AccessInsights into individual variations in nematocyst venoms from the giant jellyfish Nemopilema nomurai in the Yellow Sea
- Yang Yue
- , Huahua Yu
- & Pengcheng Li
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| Open AccessDigestion dynamics in broilers fed rapeseed meal
- E. Recoules
- , M. Lessire
- & S. Réhault-Godbert
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| Open AccessDiscovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1
- Katherine A. Vousden
- , Tomas Lundqvist
- & Tristan J. Vaughan
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| Open AccessCurcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L
- Ahlame Saidi
- , Mariana Kasabova
- & Gilles Lalmanach
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| Open AccessNovel pseudo-aspartic peptidase from the midgut of the tick Rhipicephalus microplus
- S. Lu
- , L. F. Parizi
- & A. S. Tanaka
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| Open AccessMammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases
- Konstantin Karmilin
- , Carlo Schmitz
- & Walter Stöcker
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| Open AccessTargeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery and Drug Resistance Assessment
- Liangqun Huang
- , Linfeng Li
- & Chaoping Chen
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| Open AccessA novel dry-bonding approach to reduce collagen degradation and optimize resin-dentin interfaces
- Thiago Henrique Scarabello Stape
- , Roda Seseogullari-Dirihan
- & Arzu Tezvergil-Mutluay
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| Open AccessCalpain-mediated tau fragmentation is altered in Alzheimer’s disease progression
- Hsu-Hsin Chen
- , Peter Liu
- & Marcel P. van der Brug