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| Open AccessOne-carbon metabolizing enzyme ALDH1L1 influences mitochondrial metabolism through 5-aminoimidazole-4-carboxamide ribonucleotide accumulation and serine depletion, contributing to tumor suppression
- Masato Sasaki
- , Kazuo Yamamoto
- & Nobuyuki Shibata
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| Open AccessButyrate reduces cellular magnesium absorption independently of metabolic regulation in Caco-2 human colon cells
- Lisanne M. M. Gommers
- , Pieter A. Leermakers
- & Joost G. J. Hoenderop
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| Open AccessKetone body 3-hydroxybutyrate enhances adipocyte function
- Shigeki Nishitani
- , Atsunori Fukuhara
- & Iichiro Shimomura
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| Open AccessIncreased O-GlcNAcylation promotes IGF-1 receptor/PhosphatidyI Inositol-3 kinase/Akt pathway in cervical cancer cells
- Victoria Jiménez-Castillo
- , Daniela Illescas-Barbosa
- & Tarik Issad
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| Open AccessIntracellular glucose starvation affects gingival homeostasis and autophagy
- Runbo Li
- , Hirohito Kato
- & Makoto Umeda
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| Open AccessHuman hair follicles operate an internal Cori cycle and modulate their growth via glycogen phosphorylase
- Katarzyna Figlak
- , Greg Williams
- & Michael P. Philpott
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| Open AccessIron supplementation regulates the progression of high fat diet induced obesity and hepatic steatosis via mitochondrial signaling pathways
- Naho Kitamura
- , Yoko Yokoyama
- & Mitsuhiro Watanabe
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| Open AccessA plant plasma-membrane H+-ATPase promotes yeast TORC1 activation via its carboxy-terminal tail
- Elie Saliba
- , Cecilia Primo
- & Bruno André
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| Open AccessThe nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids
- Sarah Ducastel
- , Véronique Touche
- & Sophie Lestavel
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| Open AccessSchisandrin A protects intestinal epithelial cells from deoxynivalenol-induced cytotoxicity, oxidative damage and inflammation
- Murphy L. Y. Wan
- , Paul C. Turner
- & Hani El-Nezami
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| Open AccessCD98hc (SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression
- Sara Cano-Crespo
- , Josep Chillarón
- & Manuel Palacín
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| Open AccessDirect imaging of the recruitment and phosphorylation of S6K1 in the mTORC1 pathway in living cells
- Abdullah R. Ahmed
- , Raymond J. Owens
- & Stanley W. Botchway
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| Open AccessIdentifying chondroprotective diet-derived bioactives and investigating their synergism
- Rose K. Davidson
- , Jonathan Green
- & Ian M. Clark
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| Open AccessYeast thioredoxin reductase Trr1p controls TORC1-regulated processes
- Cecilia Picazo
- , Emilia Matallana
- & Agustín Aranda
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| Open AccessBeauvericin inhibits melanogenesis by regulating cAMP/PKA/CREB and LXR-α/p38 MAPK–mediated pathways
- Seung Eun Lee
- , See-Hyoung Park
- & Jongsung Lee
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| Open AccessA short isoform of ATG7 fails to lipidate LC3/GABARAP
- M. H. Ogmundsdottir
- , V. Fock
- & E. Steingrimsson
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| Open AccessAMPK contributes to autophagosome maturation and lysosomal fusion
- Minsu Jang
- , Rackhyun Park
- & Junsoo Park
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| Open AccessPAS Kinase deficiency alters the glucokinase function and hepatic metabolism
- A. Pérez-García
- , P. Dongil
- & E. Alvarez
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| Open AccessEffects of collagen-derived bioactive peptides and natural antioxidant compounds on proliferation and matrix protein synthesis by cultured normal human dermal fibroblasts
- Suzanne Edgar
- , Blake Hopley
- & Janis Shute
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| Open AccessSESN2 negatively regulates cell proliferation and casein synthesis by inhibition the amino acid-mediated mTORC1 pathway in cow mammary epithelial cells
- Chaochao Luo
- , Shengguo Zhao
- & Nan Zheng
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| Open AccessA Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells
- Binita Das
- , Beth K. Neilsen
- & Robert E. Lewis
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| Open AccessSCFAs strongly stimulate PYY production in human enteroendocrine cells
- P. Larraufie
- , C. Martin-Gallausiaux
- & H. M. Blottiere
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| Open AccessTumor suppressor NPRL2 induces ROS production and DNA damage response
- Yinxing Ma
- , Licia Silveri
- & Svetlana Dokudovskaya
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| Open AccessFenugreek supplementation during high-fat feeding improves specific markers of metabolic health
- Eric J. Knott
- , Allison J. Richard
- & Annadora Bruce-Keller
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| Open AccessInvolvement of mTOR-autophagy in the selection of primitive mesenchymal stem cells in chitosan film 3-dimensional culture
- Hsiao-Ying Chiu
- , Yeou-Guang Tsay
- & Shih-Chieh Hung
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| Open AccessOpposite feedback from mTORC1 to H-ras and K-ras4B downstream of SREBP1
- Itziar M. D. Posada
- , Benoit Lectez
- & Daniel Abankwa
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| Open AccessResveratrol attenuates ICAM-1 expression and monocyte adhesiveness to TNF-α-treated endothelial cells: evidence for an anti-inflammatory cascade mediated by the miR-221/222/AMPK/p38/NF-κB pathway
- Chen-Wei Liu
- , Hsin-Ching Sung
- & Yuh-Lien Chen
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| Open AccessThe metabolic waste ammonium regulates mTORC2 and mTORC1 signaling
- Ahmad Merhi
- , Paul Delrée
- & Anna Maria Marini
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| Open AccessAntioxidant response is a protective mechanism against nutrient deprivation in C. elegans
- Jun Tao
- , Qin-Yi Wu
- & Cheng-Gang Zou
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| Open AccessSLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy
- Allyson L. Mayer
- , Cassandra B. Higgins
- & Brian J. DeBosch
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| Open Access13-Methylberberine, a berberine analogue with stronger anti-adipogenic effects on mouse 3T3-L1 cells
- Yit-Lai Chow
- , Mami Sogame
- & Fumihiko Sato
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| Open AccessHigh glucose upregulates BACE1-mediated Aβ production through ROS-dependent HIF-1α and LXRα/ABCA1-regulated lipid raft reorganization in SK-N-MC cells
- Hyun Jik Lee
- , Jung Min Ryu
- & Ho Jae Han
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| Open AccessGlucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine
- Naniye Mallı Cetinbas
- , Jessica Sudderth
- & Poul H. Sorensen
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| Open AccessCrosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis
- Xinlei Yu
- & Yun Chau Long
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| Open AccessGCN2 contributes to mTORC1 inhibition by leucine deprivation through an ATF4 independent mechanism
- Julien Averous
- , Sarah Lambert-Langlais
- & Pierre Fafournoux
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| Open AccessThe small GTPases Ras and Rap1 bind to and control TORC2 activity
- Ankita Khanna
- , Pouya Lotfi
- & Pascale G. Charest
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| Open AccessPerturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism
- Céline Jouffe
- , Cédric Gobet
- & Frédéric Gachon
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| Open AccessPRL-3 activates mTORC1 in Cancer Progression
- Zu Ye
- , Abdul Qader Omer Al-aidaroos
- & Qi Zeng
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| Open AccessPAK2 is an effector of TSC1/2 signaling independent of mTOR and a potential therapeutic target for Tuberous Sclerosis Complex
- Maria M. Alves
- , Gwenny M. Fuhler
- & Maikel P. Peppelenbosch
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| Open AccessLow-glucose enhances keratocyte-characteristic phenotype from corneal stromal cells in serum-free conditions
- James W. Foster
- , Ricardo M. Gouveia
- & Che J. Connon
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| Open AccessThe multikinase inhibitor Sorafenib enhances glycolysis and synergizes with glycolysis blockade for cancer cell killing
- Valentina Tesori
- , Anna Chiara Piscaglia
- & Antonio Gasbarrini
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| Open AccessThe flavonoid apigenin improves glucose tolerance through inhibition of microRNA maturation in miRNA103 transgenic mice
- Motoko Ohno
- , Chikako Shibata
- & Kazuhiko Koike