Ion channels articles within Scientific Reports

Featured

• Article
  21 March 2024 | Open Access

  Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of Na_V1.2 and Na_V1.6

  • Luis Manuel Arratia
  • , Juan David Bermudes-Contreras
  •  & Absalom Zamorano-Carrillo

• Article
  24 February 2024 | Open Access

  Behavioral analysis of kainate receptor KO mice and the role of GluK3 subunit in anxiety

  • Izumi Iida
  • , Kohtarou Konno
  •  & Miho Terunuma

• Article
  28 January 2024 | Open Access

  Kv3.4 regulates cell migration and invasion through TGF-β-induced epithelial–mesenchymal transition in A549 cells

  • Hun Ju Sim
  • , Mi Ri Kim
  •  & So Yeong Lee

• Article
  23 January 2024 | Open Access

  The combination of propylene glycol and vegetable glycerin e-cigarette aerosols induces airway inflammation and mucus hyperconcentration

  • Michael D. Kim
  • , Samuel Chung
  •  & Matthias Salathe

• Article
  08 December 2023 | Open Access

  High-throughput ligand profile characterization in novel cell lines expressing seven heterologous insect olfactory receptors for the detection of volatile plant biomarkers

  • Katalin Zboray
  • , Adam V. Toth
  •  & Peter Lukacs

• Article
  17 July 2023 | Open Access

  Determining the structure of the bacterial voltage-gated sodium channel NaChBac embedded in liposomes by cryo electron tomography and subtomogram averaging

  • Shih-Ying Scott Chang
  • , Patricia M. Dijkman
  •  & Misha Kudryashev

• Article
  15 July 2023 | Open Access

  Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer

  • Andras Szollosi
  •  & János Almássy

• Article
  01 July 2023 | Open Access

  Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators

  • Osha Roopnarine
  • , Samantha L. Yuen
  •  & David D. Thomas

• Article
  28 April 2023 | Open Access

  A blue-shifted anion channelrhodopsin from the Colpodellida alga Vitrella brassicaformis

  • Keiichi Kojima
  • , Shiho Kawanishi
  •  & Yuki Sudo

• Article
  01 April 2023 | Open Access

  Channel activity of SARS-CoV-2 viroporin ORF3a inhibited by adamantanes and phenolic plant metabolites

  • Marina Sherif Fam
  • , Christine Adel Sedky
  •  & Ulrike Breitinger

• Article
  26 October 2022 | Open Access

  Ferritin thresholds for cardiac and liver hemosiderosis in β-thalassemia patients: a diagnostic accuracy study

  • Hadi Darvishi-Khezri
  • , Aily Aliasgharian
  •  & Hossein Karami

• Article
  08 June 2022 | Open Access

  Jaw1/LRMP increases Ca²⁺ influx upon GPCR stimulation with heterogeneous effect on the activity of each ITPR subtype

  • Wataru Okumura
  • , Takuma Kozono
  •  & Atsushi Nishikawa

• Article
  08 March 2022 | Open Access

  ATP13A3 facilitates polyamine transport in human pancreatic cancer cells

  • Vandana Sekhar
  • , Thomas Andl
  •  & Otto Phanstiel IV

• Article
  11 February 2022 | Open Access

  Formation and function of OmpG or OmpA-incorporated liposomes using an in vitro translation system

  • Koki Kamiya

• Article
  21 January 2022 | Open Access

  AI-based atomic force microscopy image analysis allows to predict electrochemical impedance spectra of defects in tethered bilayer membranes

  • Tomas Raila
  • , Tadas Penkauskas
  •  & Gintaras Valinčius

• Article
  17 December 2021 | Open Access

  BrCNGC gene family in field mustard: genome-wide identification, characterization, comparative synteny, evolution and expression profiling

  • Akram Ali Baloch
  • , Agha Muhammad Raza
  •  & Kaleem U. Kakar

• Article
  15 November 2021 | Open Access

  CyFi-MAP: an interactive pathway-based resource for cystic fibrosis

  • Catarina Pereira
  • , Alexander Mazein
  •  & Andre O. Falcao

• Article
  16 July 2021 | Open Access

  Mechanisms and consequences of casein kinase II and ankyrin-3 regulation of the epithelial Na⁺ channel

  • Tarek Mohamed Abd El-Aziz
  • , Antonio G. Soares
  •  & Jonathan M. Berman

• Article
  15 July 2021 | Open Access

  Strictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvement

  • Atsushi Suzuki
  • , Akiyoshi Kunugi
  •  & Haruhide Kimura

• Article
  17 May 2021 | Open Access

  Outer membrane and phospholipid composition of the target membrane affect the antimicrobial potential of first- and second-generation lipophosphonoxins

  • Klára Látrová
  • , Noemi Havlová
  •  & Gabriela Mikušová

• Article
  13 May 2021 | Open Access

  The effects of beta-cell mass and function, intercellular coupling, and islet synchrony on \({\text {Ca}}^{2+}\) dynamics

  • Maryam Saadati
  •  & Yousef Jamali

• Article
  22 April 2021 | Open Access

  C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition

  • Giuseppe Federico Amodeo
  • , Brenda Yasie Lee
  •  & Evgeny V. Pavlov

• Article
  15 April 2021 | Open Access

  Functional NMDA receptors are expressed by human pulmonary artery smooth muscle cells

  • Yi Na Dong
  • , Fu-Chun Hsu
  •  & David R. Lynch

• Article
  14 April 2021 | Open Access

  Identification and functional analysis of a biflavone as a novel inhibitor of transient receptor potential vanilloid 4-dependent atherogenic processes

  • Mazen O. Alharbi
  • , Bidisha Dutta
  •  & Shaik O. Rahaman

• Article
  12 April 2021 | Open Access

  Preference of Proteomonas sulcata anion channelrhodopsin for NO₃⁻ revealed using a pH electrode method

  • Chihiro Kikuchi
  • , Hina Kurane
  •  & Takashi Tsukamoto

• Article
  16 February 2021 | Open Access

  Altered functional properties of the codling moth Orco mutagenized in the intracellular loop-3

  • Yuriy V. Bobkov
  • , William B. Walker III
  •  & Alberto Maria Cattaneo

• Article
  27 January 2021 | Open Access

  The carboxy terminal coiled-coil modulates Orai1 internalization during meiosis

  • Rawad Hodeify
  • , Maya Dib
  •  & Khaled Machaca

• Article
  10 December 2020 | Open Access

  Unravelling the intricate cooperativity of subunit gating in P2X2 ion channels

  • Christian Sattler
  • , Thomas Eick
  •  & Klaus Benndorf

• Article
  20 October 2020 | Open Access

  Toxic oligomers of the amyloidogenic HypF-N protein form pores in mitochondrial membranes

  • Maria Ylenia Farrugia
  • , Mario Caruana
  •  & Neville Vassallo

• Article
  01 October 2020 | Open Access

  A structure-based computational workflow to predict liability and binding modes of small molecules to hERG

  • Subha Kalyaanamoorthy
  • , Shawn M. Lamothe
  •  & Khaled H. Barakat

• Article
  29 September 2020 | Open Access

  Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca²⁺ uptake in photoreceptor mitochondria

  • Celia M. Bisbach
  • , Rachel A. Hutto
  •  & Susan E. Brockerhoff

• Article
  25 August 2020 | Open Access

  Highly functionalized β-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity

  • M.Ángeles Bonache
  • , Cristina Martín-Escura
  •  & Rosario González-Muñiz

• Article
  12 August 2020 | Open Access

  Insights on small molecule binding to the Hv1 proton channel from free energy calculations with molecular dynamics simulations

  • Victoria T. Lim
  • , Andrew D. Geragotelis
  •  & Douglas J. Tobias

• Article
  04 August 2020 | Open Access

  Uncovering a possible role of reactive oxygen species in magnetogenetics

  • Matthew I. Brier
  • , Jordan W. Mundell
  •  & Jonathan S. Dordick

• Article
  24 July 2020 | Open Access

  Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in Ca_V3 T-type channels alter the passage and block of monovalent and divalent ions

  • Wendy Guan
  • , Robert F. Stephens
  •  & J. David Spafford

• Article
  09 July 2020 | Open Access

  Molecular and cellular correlates in Kv channel clustering: entropy-based regulation of cluster ion channel density

  • Limor Lewin
  • , Esraa Nsasra
  •  & Ofer Yifrach

• Article
  17 June 2020 | Open Access

  Transient Receptor Potential Vanilloid channel regulates fibroblast differentiation and airway remodeling by modulating redox signals through NADPH Oxidase 4

  • Nosayba Al-Azzam
  • , Lakshminarayan Reddy Teegala
  •  & Sailaja Paruchuri

• Article
  19 May 2020 | Open Access

  Drosophila taste neurons as an agonist-screening platform for P2X receptors

  • Leanne Grimes
  • , Julia Griffiths
  •  & Wynand van der Goes van Naters

• Article
  10 April 2020 | Open Access

  Structure-based engineering of anti-GFP nanobody tandems as ultra-high-affinity reagents for purification

  • Ziyue Zhang
  • , Yao Wang
  •  & Motoyuki Hattori

• Article
  11 March 2020 | Open Access

  Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities

  • Johara Boldrini-França
  • , Ernesto Lopes Pinheiro-Junior
  •  & Jan Tytgat

• Article
  06 March 2020 | Open Access

  Selective Binding of HSC70 and its Co-Chaperones to Structural Hotspots on CFTR

  • Imad Baaklini
  • , Conrado de Campos Gonçalves
  •  & Jason C. Young

• Article
  02 March 2020 | Open Access

  Complex approach for analysis of snake venom α-neurotoxins binding to HAP, the high-affinity peptide

  • Denis S. Kudryavtsev
  • , Valentin М. Tabakmakher
  •  & Victor I. Tsetlin

• Article
  24 January 2020 | Open Access

  Nanodisc technology facilitates identification of monoclonal antibodies targeting multi-pass membrane proteins

  • Bernd Gardill
  • , Jerry Huang
  •  & Christy A. Thomson

• Article
  21 January 2020 | Open Access

  Cation permeability in CorA family of proteins

  • Artem Stetsenko
  •  & Albert Guskov

• Article
  09 January 2020 | Open Access

  Structure-activity relationship studies of four novel 4-aminopyridine K⁺ channel blockers

  • Sofia Rodríguez-Rangel
  • , Alyssa D. Bravin
  •  & Jorge E. Sánchez-Rodríguez

• Article
  17 December 2019 | Open Access

  Ca⁽²⁺⁾N It Be Measured? Detection of Extramitochondrial Calcium Movement With High-Resolution FluoRespirometry

  • Anna Nászai
  • , Emil Terhes
  •  & László Juhász

• Article
  16 December 2019 | Open Access

  A muscular hypotonia-associated STIM1 mutant at R429 induces abnormalities in intracellular Ca²⁺ movement and extracellular Ca²⁺ entry in skeletal muscle

  • Jun Hee Choi
  • , Mei Huang
  •  & Eun Hui Lee

• Article
  13 December 2019 | Open Access

  Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations

  • Changyi Ji
  • , Yao Li
  •  & Tingting Yang

• Article
  28 November 2019 | Open Access

  Curcumin enhances cisplatin-induced human laryngeal squamous cancer cell death through activation of TRPM2 channel and mitochondrial oxidative stress

  • Sinem Gökçe Kütük
  • , Gökçen Gökçe
  •  & Mustafa Nazıroğlu

• Article
  27 November 2019 | Open Access

  Nanomolar-potency ‘co-potentiator’ therapy for cystic fibrosis caused by a defined subset of minimal function CFTR mutants

  • Puay-Wah Phuan
  • , Joseph-Anthony Tan
  •  & Alan S. Verkman