Ion channel signalling articles within Scientific Reports

Featured

• Article
  06 May 2024 | Open Access

  The local mechanosensitive response of primary cardiac fibroblasts is influenced by the microenvironment mechanics

  • Nicoletta Braidotti
  • , Giorgia Demontis
  •  & Dan Cojoc

• Article
  21 March 2024 | Open Access

  Mechanosensitive TRPV4 channel guides maturation and organization of the bilayered mammary epithelium

  • Kärki Tytti
  • , Koskimäki Sanna
  •  & Tojkander Sari

• Article
  12 June 2023 | Open Access

  Mechanical-induced bone remodeling does not depend on Piezo1 in dentoalveolar hard tissue

  • Cita Nottmeier
  • , Josef Lavicky
  •  & Julian Petersen

• Article
  07 December 2022 | Open Access

  The mitochondrial Ca²⁺ uniporter channel synergizes with fluid shear stress to induce mitochondrial Ca²⁺ oscillations

  • Akshar Patel
  • , Matthew Simkulet
  •  & B. Rita Alevriadou

• Article
  03 November 2022 | Open Access

  Butyrate reduces cellular magnesium absorption independently of metabolic regulation in Caco-2 human colon cells

  • Lisanne M. M. Gommers
  • , Pieter A. Leermakers
  •  & Joost G. J. Hoenderop

• Article
  21 May 2021 | Open Access

  Glucose and NAADP trigger elementary intracellular β-cell Ca²⁺ signals

  • Paula Maria Heister
  • , Trevor Powell
  •  & Antony Galione

• Article
  08 April 2021 | Open Access

  Mitochondria-targeted antioxidant protects against irradiation-induced salivary gland hypofunction

  • Xibao Liu
  • , Krishna P. Subedi
  •  & Indu Ambudkar

• Article
  16 March 2021 | Open Access

  Both IRBIT and long-IRBIT bind to and coordinately regulate Cl⁻/HCO₃⁻ exchanger AE2 activity through modulating the lysosomal degradation of AE2

  • Ryo Itoh
  • , Naoya Hatano
  •  & Akihiro Mizutani

• Article
  13 January 2021 | Open Access

  Modulation of cAMP metabolism for CFTR potentiation in human airway epithelial cells

  • Jenny P. Nguyen
  • , Matthew Bianca
  •  & Jeremy A. Hirota

• Article
  24 June 2020 | Open Access

  Role of PKC in the Regulation of the Human Kidney Chloride Channel ClC-Ka

  • Andrea Gerbino
  • , Roberta De Zio
  •  & Monica Carmosino

• Article
  26 May 2020 | Open Access

  Connexin43 and connexin50 channels exhibit different permeability to the second messenger inositol triphosphate

  • Virginijus Valiunas
  •  & Thomas W. White

• Article
  14 May 2020 | Open Access

  Chronic Sympathetic Hyperactivity Triggers Electrophysiological Remodeling and Disrupts Excitation-Contraction Coupling in Heart

  • Humberto C. Joca
  • , Artur Santos‐Miranda
  •  & Jader S. Cruz

• Article
  07 April 2020 | Open Access

  The Na/K-ATPase α1 and c-Src form signaling complex under native condition: A crosslinking approach

  • Ying Nie
  • , Fang Bai
  •  & Jiang Liu

• Article
  18 February 2020 | Open Access

  Transient Cell Membrane Disruptions induce Calcium Waves in Corneal Keratocytes

  • Zhong Chen
  • , Xiaowen Lu
  •  & Mitchell A. Watsky

• Article
  10 December 2019 | Open Access

  Pannexin 3 ER Ca²⁺ channel gating is regulated by phosphorylation at the Serine 68 residue in osteoblast differentiation

  • Masaki Ishikawa
  • , Geneva Williams
  •  & Yoshihiko Yamada

• Article
  06 December 2019 | Open Access

  Relaxin reverses maladaptive remodeling of the aged heart through Wnt-signaling

  • Brian Martin
  • , Beth Gabris
  •  & Guy Salama

• Article
  06 December 2019 | Open Access

  Validation of antibodies for the specific detection of human TRPA1

  • H. S. Virk
  • , M. Z. Rekas
  •  & P. Bradding

• Article
  12 November 2019 | Open Access

  ATP amplifies NADPH-dependent and -independent neutrophil extracellular trap formation

  • Aderonke Sofoluwe
  • , Marc Bacchetta
  •  & Marc Chanson

• Article
  04 November 2019 | Open Access

  Prominin-1 Modulates Rho/ROCK-Mediated Membrane Morphology and Calcium-Dependent Intracellular Chloride Flux

  • Akiko Hori
  • , Kenji Nishide
  •  & Noriaki Sasai

• Article
  01 October 2019 | Open Access

  The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2

  • Lei Bao
  • , Fernanda Festa
  •  & Barbara A. Miller

• Article
  01 May 2019 | Open Access

  Shear force modulates the activity of acid-sensing ion channels at low pH or in the presence of non-proton ligands

  • Daniel Barth
  •  & Martin Fronius

• Article
  30 April 2019 | Open Access

  Temperature-dependent increase in the calcium sensitivity and acceleration of activation of ANO6 chloride channel variants

  • Haiyue Lin
  • , Ikhyun Jun
  •  & Joo Hyun Nam

• Article
  21 March 2019 | Open Access

  Different substrate specificities of the two ADPR binding sites in TRPM2 channels of Nematostella vectensis and the role of IDPR

  • Frank J. P. Kühn
  • , Joanna M. Watt
  •  & Andreas Lückhoff

• Article
  01 March 2019 | Open Access

  Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7

  • Stefan M. Bidula
  • , Brett A. Cromer
  •  & Leanne Stokes

• Article
  24 September 2018 | Open Access

  Enantiomeric Aβ peptides inhibit the fluid shear stress response of PIEZO1

  • Mohammad M. Maneshi
  • , Lynn Ziegler
  •  & Philip A. Gottlieb

• Article
  11 September 2018 | Open Access

  Zinc uptake promotes myoblast differentiation via Zip7 transporter and activation of Akt signalling transduction pathway

  • Hayk Mnatsakanyan
  • , Roser Sabater i Serra
  •  & Manuel Salmerón-Sánchez

• Article
  13 August 2018 | Open Access

  Differential interactions of bacterial lipopolysaccharides with lipid membranes: implications for TRPA1-mediated chemosensation

  • Justyna B. Startek
  • , Karel Talavera
  •  & Yeranddy A. Alpizar

• Article
  25 July 2018 | Open Access

  Spatially restricted subcellular Ca²⁺ signaling downstream of store-operated calcium entry encoded by a cortical tunneling mechanism

  • Raphael Courjaret
  • , Maya Dib
  •  & Khaled Machaca

• Article
  18 June 2018 | Open Access

  Muscarinic receptor-induced contractions of the detrusor are impaired in TRPC4 deficient mice

  • Caoimhin S. Griffin
  • , Keith D. Thornbury
  •  & Gerard P. Sergeant

• Article
  12 June 2018 | Open Access

  The P2X7 receptor and pannexin-1 are involved in glucose-induced autocrine regulation in β-cells

  • Marco Tozzi
  • , Anna T. Larsen
  •  & Ivana Novak

• Article
  09 May 2018 | Open Access

  Disruption of neonatal cardiomyocyte physiology following exposure to bisphenol-a

  • Manelle Ramadan
  • , Meredith Sherman
  •  & Nikki Gillum Posnack

• Article
  16 April 2018 | Open Access

  Involvement of AMP-activated Protein Kinase (AMPK) in Regulation of Cell Membrane Potential in a Gastric Cancer Cell Line

  • Lin Zhu
  • , Xiao-jian Yu
  •  & Wei-Jun Yang

• Article
  10 April 2018 | Open Access

  Stimulation of TLR3 triggers release of lysosomal ATP in astrocytes and epithelial cells that requires TRPML1 channels

  • Jonathan M. Beckel
  • , Néstor Más Gómez
  •  & Claire H. Mitchell

• Article
  22 February 2018 | Open Access

  Gα_i-mediated TRPC4 activation by polycystin-1 contributes to endothelial function via STAT1 activation

  • Misun Kwak
  • , Chansik Hong
  •  & Insuk So

• Article
  18 January 2018 | Open Access

  Cytokine-mediated changes in K⁺ channel activity promotes an adaptive Ca²⁺ response that sustains β-cell insulin secretion during inflammation

  • Matthew T. Dickerson
  • , Avery M. Bogart
  •  & David A. Jacobson

• Article
  16 January 2018 | Open Access

  EPHB6 and testosterone in concert regulate epinephrine release by adrenal gland chromaffin cells

  • Yujia Wang
  • , Wei Shi
  •  & Jiangping Wu

• Article
  16 January 2018 | Open Access

  Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling

  • Raymond W. Wong
  • , Clifford A. Lingwood
  •  & Alan Cochrane

• Article
  08 November 2017 | Open Access

  Cellular information dynamics through transmembrane flow of ions

  • Robert A. Gatenby
  •  & B. Roy Frieden

• Article
  26 October 2017 | Open Access

  Organelle membrane derived patches: reshaping classical methods for new targets

  • George Shapovalov
  • , Abigaël Ritaine
  •  & Natalia Prevarskaya

• Article
  23 October 2017 | Open Access

  Functional expression and pharmaceutical efficacy of cardiac-specific ion channels in human embryonic stem cell-derived cardiomyocytes

  • Han Sol Kim
  • , Jung Won Yoon
  •  & Won Sun Park

• Article
  16 October 2017 | Open Access

  Store-operated Ca²⁺ Entry Facilitates the Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Gastric Cancer Cells

  • Jhen-Hong Wong
  • , Kuo-Hao Ho
  •  & Wei-Chiao Chang

• Article
  07 September 2017 | Open Access

  Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages

  • Caterina Di Pietro
  • , Ping-xia Zhang
  •  & Emanuela M. Bruscia

• Article
  05 September 2017 | Open Access

  Role of Smad3 and p38 Signalling in Cigarette Smoke-induced CFTR and BK dysfunction in Primary Human Bronchial Airway Epithelial Cells

  • Juliette Sailland
  • , Astrid Grosche
  •  & Matthias Salathe

• Article
  05 September 2017 | Open Access

  Structural determinants of 5′,6′-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel

  • Alejandro Berna-Erro
  • , Mercè Izquierdo-Serra
  •  & Miguel A. Valverde

• Article
  29 August 2017 | Open Access

  Integrative Approach with Electrophysiological and Theoretical Methods Reveals a New Role of S4 Positively Charged Residues in PKD2L1 Channel Voltage-Sensing

  • Tomohiro Numata
  • , Kunichika Tsumoto
  •  & Yasuo Mori

• Article
  10 August 2017 | Open Access

  Magnesium Chloride promotes Osteogenesis through Notch signaling activation and expansion of Mesenchymal Stem Cells

  • Juan M. Díaz-Tocados
  • , Carmen Herencia
  •  & Juan R. Muñoz-Castañeda

• Article
  02 August 2017 | Open Access

  Compensatory Vasodilator Mechanisms in the Ophthalmic Artery of Endothelial Nitric Oxide Synthase Gene Knockout Mice

  • Caroline Manicam
  • , Natalja Ginter
  •  & Adrian Gericke

• Article
  27 July 2017 | Open Access

  CALHM1-Mediated ATP Release and Ciliary Beat Frequency Modulation in Nasal Epithelial Cells

  • Alan D. Workman
  • , Ryan M. Carey
  •  & Noam A. Cohen

• Article
  21 July 2017 | Open Access

  Structural determinants at the M2 muscarinic receptor modulate the RGS4-GIRK response to pilocarpine by impairment of the receptor voltage sensitivity

  • I-Shan Chen
  • , Kazuharu Furutani
  •  & Yoshihisa Kurachi

• Article
  28 June 2017 | Open Access

  K_ca3.1 Activation Via P2y₂ Purinergic Receptors Promotes Human Ovarian Cancer Cell (Skov-3) Migration

  • L. Robles-Martínez
  • , E. Garay
  •  & R. O. Arellano