Induced pluripotent stem cells articles within Scientific Reports

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• Article
  28 May 2024 | Open Access

  Development of an iPSC-derived tissue-resident macrophage-based platform for the in vitro immunocompatibility assessment of human tissue engineered matrices

  • Nikolaos Poulis
  • , Marcy Martin
  •  & Emanuela S. Fioretta

• Article
  16 April 2024 | Open Access

  SARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids

  • Chiu Wang Chau
  • , Alex To
  •  & Ryohichi Sugimura

• Article
  27 March 2024 | Open Access

  Detection of biomagnetic signals from induced pluripotent stem cell-derived cardiomyocytes using deep learning with simulation data

  • Takeshi Yamaguchi
  • , Yoshiaki Adachi
  •  & Masaki Tanaka

• Article
  26 March 2024 | Open Access

  Nilotinib-induced alterations in endothelial cell function recapitulate clinical vascular phenotypes independent of ABL1

  • Emily A. Pinheiro
  • , Jean-Marc DeKeyser
  •  & Paul W. Burridge

• Article
  12 March 2024 | Open Access

  Characterization of human iPSC-derived sensory neurons and their functional assessment using multi electrode array

  • Minami Hiranuma
  • , Yuichi Okuda
  •  & Tomohisa Watanabe

• Article
  08 February 2024 | Open Access

  Graft-derived neurons and bystander effects are maintained for six months after human iPSC-derived NESC transplantation in mice’s cerebella

  • Liliana S. Mendonça
  • , Daniel Henriques
  •  & Luís Pereira de Almeida

• Article
  08 February 2024 | Open Access

  Establishment of African pygmy mouse induced pluripotent stem cells using defined doxycycline inducible transcription factors

  • Sumito Matsuya
  • , Kaoru Fujino
  •  & Kiyoshi Kano

• Article
  08 February 2024 | Open Access

  Human archetypal pluripotent stem cells differentiate into trophoblast stem cells via endogenous BMP5/7 induction without transitioning through naive state

  • Ethan Tietze
  • , Andre Rocha Barbosa
  •  & Jennifer A. Erwin

• Article
  07 February 2024 | Open Access

  In situ monolayer patch clamp of acutely stimulated human iPSC-derived cardiomyocytes promotes consistent electrophysiological responses to SK channel inhibition

  • Andrew S. Butler
  • , Raimondo Ascione
  •  & Jules C. Hancox

• Article
  31 January 2024 | Open Access

  Modeling mutation-specific arrhythmogenic phenotypes in isogenic human iPSC-derived cardiac tissues

  • Thomas L. Maurissen
  • , Masahide Kawatou
  •  & Knut Woltjen

• Article
  29 January 2024 | Open Access

  Integration-free induced pluripotent stem cells from three endangered Southeast Asian non-human primate species

  • Qiuye Bao
  • , Nicole Liling Tay
  •  & Chou Chai

• Article
  13 December 2023 | Open Access

  Combination of melt-electrospun poly-ε-caprolactone scaffolds and hepatocyte-like cells from footprint-free hiPSCs to create 3D biohybrid constructs for liver tissue engineering

  • Josefin Weber
  • , Carsten Linti
  •  & Meltem Avci-Adali

• Article
  11 December 2023 | Open Access

  Efficient gene editing in induced pluripotent stem cells enabled by an inducible adenine base editor with tunable expression

  • Krittika Nandy
  • , Dinesh Babu
  •  & Shaji R. Velayudhan

• Article
  04 December 2023 | Open Access

  SARS-CoV-2 spike receptor-binding domain is internalized and promotes protein ISGylation in human induced pluripotent stem cell-derived cardiomyocytes

  • Shota Okuno
  • , Shuichiro Higo
  •  & Yasushi Sakata

• Article
  30 September 2023 | Open Access

  Estimating residual undifferentiated cells in human chemically induced pluripotent stem cell derived islets using lncRNA as biomarkers

  • Yandan Wu
  • , Zhenzhen Zhang
  •  & Yue Pu

• Article
  21 September 2023 | Open Access

  Effect of extracellular vesicles derived from induced pluripotent stem cells on mesangial cells underwent a model of fibrosis in vitro

  • Bruno Aristides dos Santos Bronel
  • , Edgar Maquigussa
  •  & Antônio da Silva Novaes

• Article
  24 August 2023 | Open Access

  Development of a three-dimensional organoid model to explore early retinal phenotypes associated with Alzheimer’s disease

  • Sailee S. Lavekar
  • , Jade Harkin
  •  & Jason S. Meyer

• Article
  11 May 2023 | Open Access

  A CRISPR-engineered isogenic model of the 22q11.2 A-B syndromic deletion

  • Neha Paranjape
  • , Yu-Hsiu T. Lin
  •  & Arun P. Wiita

• Article
  14 April 2023 | Open Access

  Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis

  • Frances M. Bashore
  • , Ariana B. Marquez
  •  & Alison D. Axtman

• Article
  27 February 2023 | Open Access

  Remote-refocusing light-sheet fluorescence microscopy enables 3D imaging of electromechanical coupling of hiPSC-derived and adult cardiomyocytes in co-culture

  • L. Dvinskikh
  • , H. Sparks
  •  & C. Dunsby

• Article
  28 December 2022 | Open Access

  Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy

  • Francesca Margara
  • , Yiangos Psaras
  •  & Alfonso Bueno-Orovio

• Article
  30 November 2022 | Open Access

  Creating a kidney organoid-vasculature interaction model using a novel organ-on-chip system

  • Amanda Bas-Cristóbal Menéndez
  • , Z. Du
  •  & M. J. Hoogduijn

• Article
  04 November 2022 | Open Access

  iPSC-neural crest derived cells embedded in 3D printable bio-ink promote cranial bone defect repair

  • Juliane D. Glaeser
  • , Xianchao Bao
  •  & Dmitriy Sheyn

• Article
  17 October 2022 | Open Access

  Differentiation of human induced pluripotent stem cells into hypothalamic vasopressin neurons with minimal exogenous signals and partial conversion to the naive state

  • Hajime Ozaki
  • , Hidetaka Suga
  •  & Hiroshi Arima

• Article
  16 September 2022 | Open Access

  Customized strategies for high-yield purification of retinal pigment epithelial cells differentiated from different stem cell sources

  • Kakkad Regha
  • , Mayuri Bhargava
  •  & Xinyi Su

• Article
  23 July 2022 | Open Access

  Human iPSC co-culture model to investigate the interaction between microglia and motor neurons

  • Björn F. Vahsen
  • , Elizabeth Gray
  •  & Kevin Talbot

• Article
  14 June 2022 | Open Access

  Establishment and characterization of a novel human induced pluripotent stem cell line stably expressing the iRFP720 reporter

  • Anita Fehér
  • , Andrea Schnúr
  •  & András Dinnyés

• Article
  05 May 2022 | Open Access

  Hyperexcitability in young iPSC-derived C9ORF72 mutant motor neurons is associated with increased intracellular calcium release

  • Sarah Burley
  • , Dayne A. Beccano-Kelly
  •  & Richard Wade-Martins

• Article
  19 April 2022 | Open Access

  Preferential stimulation of melanocytes by M2 macrophages to produce melanin through vascular endothelial growth factor

  • Heeju Han
  • , Yena Kim
  •  & Ji Hyeon Ju

• Article
  02 March 2022 | Open Access

  Metabolites of soil microorganisms modulate amyloid β production in Alzheimer’s neurons

  • Takayuki Kondo
  • , Tsuyoshi Yamamoto
  •  & Haruhisa Inoue

• Article
  15 November 2021 | Open Access

  Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons

  • Aaron M. Earley
  • , Lena F. Burbulla
  •  & Rajeshwar Awatramani

• Article
  03 November 2021 | Open Access

  Developmental defects and impaired network excitability in a cerebral organoid model of KCNJ11 p.V59M-related neonatal diabetes

  • Gokhan Dalgin
  • , Andrew K. Tryba
  •  & Alfredo J. Garcia III

• Article
  15 October 2021 | Open Access

  RETRACTED ARTICLE: Human induced pluripotent stem cell-derived platelets loaded with lapatinib effectively target HER2+ breast cancer metastasis to the brain

  • Arunoday Bhan
  • , Khairul Ansari
  •  & Rahul Jandial

• Article
  23 September 2021 | Open Access

  Neuronal mitochondrial dysfunction in sporadic amyotrophic lateral sclerosis is developmentally regulated

  • Tanisha Singh
  • , Yuanyuan Jiao
  •  & Diane L. Carlisle

• Article
  30 August 2021 | Open Access

  N-Acetylcysteine prevents amyloid-β secretion in neurons derived from human pluripotent stem cells with trisomy 21

  • Hiromitsu Toshikawa
  • , Akihiro Ikenaka
  •  & Megumu K. Saito

• Article
  25 August 2021 | Open Access

  Na_V1.5 knockout in iPSCs: a novel approach to study Na_V1.5 variants in a human cardiomyocyte environment

  • Marion Pierre
  • , Mohammed Djemai
  •  & Mohamed Chahine

• Article
  30 June 2021 | Open Access

  Angiopoietins stimulate pancreatic islet development from stem cells

  • Soujanya S. Karanth
  • , Shuofei Sun
  •  & Sha Jin

• Article
  21 June 2021 | Open Access

  High-resolution transcriptional landscape of xeno-free human induced pluripotent stem cell-derived cerebellar organoids

  • Samuel Nayler
  • , Devika Agarwal
  •  & Esther B. E. Becker

• Article
  05 May 2021 | Open Access

  CD82 is a marker to isolate β cell precursors from human iPS cells and plays a role for the maturation of β cells

  • Ami Watanabe
  • , Anna Tanaka
  •  & Atsushi Miyajima

• Article
  30 April 2021 | Open Access

  CB₁ antagonism increases excitatory synaptogenesis in a cortical spheroid model of fetal brain development

  • Alexis Papariello
  • , David Taylor
  •  & Karen Litwa

• Article
  19 April 2021 | Open Access

  Induced pluripotent stem cells from subjects with Lesch-Nyhan disease

  • Diane J. Sutcliffe
  • , Ashok R. Dinasarapu
  •  & H. A. Jinnah

• Article
  05 April 2021 | Open Access

  Ionizing radiation exposure of stem cell-derived chondrocytes affects their gene and microRNA expression profiles and cytokine production

  • Ewelina Stelcer
  • , Katarzyna Kulcenty
  •  & Wiktoria Maria Suchorska

• Article
  25 February 2021 | Open Access

  Characterization of mitochondrial health from human peripheral blood mononuclear cells to cerebral organoids derived from induced pluripotent stem cells

  • Angela Duong
  • , Alesya Evstratova
  •  & Ana C. Andreazza

• Article
  19 February 2021 | Open Access

  Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages

  • Elena Navarro-Guerrero
  • , Chwen Tay
  •  & Daniel Ebner

• Article
  18 February 2021 | Open Access

  Human induced pluripotent stem cell-based platform for modeling cardiac ischemia

  • Martta Häkli
  • , Joose Kreutzer
  •  & Mari Pekkanen-Mattila

• Article
  10 February 2021 | Open Access

  Pluripotency and immunomodulatory signatures of canine induced pluripotent stem cell-derived mesenchymal stromal cells are similar to harvested mesenchymal stromal cells

  • Arash Shahsavari
  • , Prasanna Weeratunga
  •  & Deanne J. Whitworth

• Article
  04 February 2021 | Open Access

  CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes

  • Orlando Chirikian
  • , William R. Goodyer
  •  & Sean M. Wu

• Article
  27 January 2021 | Open Access

  Salicylic diamines selectively eliminate residual undifferentiated cells from pluripotent stem cell-derived cardiomyocyte preparations

  • Karsten Burkert
  • , Hadiseh Taheri
  •  & Tomo Šarić

• Article
  23 November 2020 | Open Access

  Quantitative proteomics reveal lineage-specific protein profiles in iPSC-derived Marfan syndrome smooth muscle cells

  • Cristiana Iosef
  • , Albert J. Pedroza
  •  & Michael P. Fischbein

• Article
  05 November 2020 | Open Access

  Establishment of a heart-on-a-chip microdevice based on human iPS cells for the evaluation of human heart tissue function

  • Mosha Abulaiti
  • , Yaxiaer Yalikun
  •  & Hidetoshi Masumoto