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| Open AccessPhosphomimetic cardiac myosin-binding protein C partially rescues a cardiomyopathy phenotype in murine engineered heart tissue
- Alexander Dutsch
- , Paul J. M. Wijnker
- & Giulia Mearini
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| Open AccessProtection from noise-induced cochlear synaptopathy by virally mediated overexpression of NT3
- Ken Hashimoto
- , Tyler T. Hickman
- & M. Charles Liberman
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| Open AccessMacrophage polarization impacts tunneling nanotube formation and intercellular organelle trafficking
- Spencer Goodman
- , Swati Naphade
- & Stephanie Cherqui
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| Open AccessThe R229Q mutation of Rag2 does not characterize severe immunodeficiency in mice
- Young Jin
- , Ara Lee
- & Sang-Jun Ha
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| Open AccessA note on retrograde gene transfer efficiency and inflammatory response of lentiviral vectors pseudotyped with FuG-E vs. FuG-B2 glycoproteins
- Soshi Tanabe
- , Shiori Uezono
- & Masahiko Takada
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| Open AccessTargeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection
- Yulia Lampi
- , Dominique Van Looveren
- & Rik Gijsbers
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| Open AccessAssociation of PXR and CAR Polymorphisms and Antituberculosis Drug-Induced Hepatotoxicity
- Yu Wang
- , Xi Xiang
- & Jian-Qing He
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| Open AccessSuppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9
- Dmitry Kostyushev
- , Anastasiya Kostyusheva
- & Vladimir Chulanov
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| Open AccessSoluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer
- Carlotta Spano
- , Giulia Grisendi
- & Massimo Dominici
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| Open AccessDelivery of mRNA to platelets using lipid nanoparticles
- S. Novakowski
- , K. Jiang
- & C. Kastrup
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| Open AccessTRIAMF: A New Method for Delivery of Cas9 Ribonucleoprotein Complex to Human Hematopoietic Stem Cells
- Jonathan Yen
- , Michael Fiorino
- & Yi Yang
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Article
| Open AccessCharacterizing the protective effects of SHLP2, a mitochondrial-derived peptide, in macular degeneration
- Sonali Nashine
- , Pinchas Cohen
- & M. Cristina Kenney
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| Open AccessOptogenetic Peripheral Nerve Immunogenicity
- Benjamin E. Maimon
- , Maurizio Diaz
- & Hugh M. Herr
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| Open AccessEngineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease
- Matthew J. Johnson
- , Kanut Laoharawee
- & Branden S. Moriarity
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| Open AccessSelective targeting of KRAS oncogenic alleles by CRISPR/Cas9 inhibits proliferation of cancer cells
- Wookjae Lee
- , Joon Ho Lee
- & Duhee Bang
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| Open AccessDevelopment of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD
- Christopher A. Reid
- , Emily R. Nettesheim
- & Daniel M. Lipinski
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| Open AccessPEGylation of polypropylenimine dendrimers: effects on cytotoxicity, DNA condensation, gene delivery and expression in cancer cells
- Sukrut Somani
- , Partha Laskar
- & Christine Dufès
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Article
| Open AccessGenome-wide association study identifies genes associated with neuropathy in patients with head and neck cancer
- Cielito C. Reyes-Gibby
- , Jian Wang
- & Sanjay Shete
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| Open AccessHIV-1 inhibition in cells with CXCR4 mutant genome created by CRISPR-Cas9 and piggyBac recombinant technologies
- Shuai Liu
- , Qiankun Wang
- & Shuliang Chen
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| Open AccessOverexpression of Cx43 in cells of the myocardial scar: Correction of post-infarct arrhythmias through heterotypic cell-cell coupling
- Wilhelm Roell
- , Alexandra M. Klein
- & Bernd K. Fleischmann
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| Open AccessSmall nuclear RNA-mediated modulation of splicing reveals a therapeutic strategy for a TREM2 mutation and its post-transcriptional regulation
- Motoaki Yanaizu
- , Kenji Sakai
- & Jun-ichi Satoh
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| Open AccessLentiPro26: novel stable cell lines for constitutive lentiviral vector production
- H. A. Tomás
- , A. F. Rodrigues
- & A. S. Coroadinha
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| Open AccessDelivery of exogenous mitochondria via centrifugation enhances cellular metabolic function
- Mi Jin Kim
- , Jung Wook Hwang
- & Yong-Soo Choi
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| Open AccessHepatocellular carcinoma-targeting oncolytic adenovirus overcomes hypoxic tumor microenvironment and effectively disperses through both central and peripheral tumor regions
- A-Rum Yoon
- , JinWoo Hong
- & Chae-Ok Yun
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| Open AccessBaculovirus-assisted Reovirus Infection in Monolayer and Spheroid Cultures of Glioma cells
- Iris J. C. Dautzenberg
- , Sanne K. van den Hengel
- & Rob C. Hoeben
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| Open AccessCRISPR/Cas9 delivery with one single adenoviral vector devoid of all viral genes
- Eric Ehrke-Schulz
- , Maren Schiwon
- & Anja Ehrhardt
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| Open AccessDeep mutational scanning of S. pyogenes Cas9 reveals important functional domains
- Jeffrey M. Spencer
- & Xiaoliu Zhang
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| Open AccessTowards personalised allele-specific CRISPR gene editing to treat autosomal dominant disorders
- Kathleen A. Christie
- , David G. Courtney
- & C. B. Tara Moore
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| Open AccessSite Specific Modification of Adeno-Associated Virus Enables Both Fluorescent Imaging of Viral Particles and Characterization of the Capsid Interactome
- Jayanth S. Chandran
- , Paul S. Sharp
- & Mimoun Azzouz
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| Open AccessGene delivery of hypoxia-inducible VEGF targeting collagen effectively improves cardiac function after myocardial infarction
- Jing-Bo Xia
- , Hai-Yan Wu
- & Xu-Feng Qi
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| Open AccessAssessment of selected media supplements to improve F/HN lentiviral vector production yields
- Jean-François Gélinas
- , Lee A. Davies
- & Stephen C. Hyde
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Article
| Open AccessDelivery of large transgene cassettes by foamy virus vector
- Nathan Paul Sweeney
- , Jinhong Meng
- & Myra McClure
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| Open AccessIn vivo genetic manipulation of inner ear connexin expression by bovine adeno-associated viral vectors
- Giulia Crispino
- , Fabian Galindo Ramirez
- & Fabio Mammano
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| Open AccessGene-based Therapy in a Mouse Model of Blue Cone Monochromacy
- Yuxin Zhang
- , Wen-Tao Deng
- & Ji-jing Pang
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| Open AccessDeletion of the B-B’ and C-C’ regions of inverted terminal repeats reduces rAAV productivity but increases transgene expression
- Qingzhang Zhou
- , Wenhong Tian
- & Xiaobing Wu
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| Open AccessAcoustic-transfection for genomic manipulation of single-cells using high frequency ultrasound
- Sangpil Yoon
- , Pengzhi Wang
- & K. Kirk Shung
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| Open AccessCRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia B mice
- Tsukasa Ohmori
- , Yasumitsu Nagao
- & Yoichi Sakata
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| Open AccessRecombinant Adeno-Associated Virus-Mediated Expression of Methamphetamine Antibody Attenuates Methamphetamine-Induced Hyperactivity in Mice
- Yun-Hsiang Chen
- , Kuo-Jen Wu
- & Yun Wang
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| Open AccessReprogramming MHC specificity by CRISPR-Cas9-assisted cassette exchange
- William Kelton
- , Ann Cathrin Waindok
- & Sai T. Reddy
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| Open AccessHigh Plasma Lipid Levels Reduce Efficacy of Adenovirus-Mediated Gene Therapy
- A. M. Kivelä
- , J. Huusko
- & S. Ylä-Herttuala
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| Open AccessChromatin states shape insertion profiles of the piggyBac, Tol2 and Sleeping Beauty transposons and murine leukemia virus
- Junko Yoshida
- , Keiko Akagi
- & Kyoji Horie
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| Open AccessAdeno-associated virus serotype rh.10 displays strong muscle tropism following intraperitoneal delivery
- Jianzhong Ai
- , Jia Li
- & Guangping Gao
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| Open AccessRNA activation of haploinsufficient Foxg1 gene in murine neocortex
- Cristina Fimiani
- , Elisa Goina
- & Antonello Mallamaci
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| Open AccessDeregulation of the miR-16-KRAS axis promotes colorectal cancer
- Chaoying You
- , Hongwei Liang
- & Yi Ba
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| Open AccessLent-On-Plus Lentiviral vectors for conditional expression in human stem cells
- Karim Benabdellah
- , Pilar Muñoz
- & Francisco Martin
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| Open AccessRetargeted Foamy Virus Vectors Integrate Less Frequently Near Proto-oncogenes
- Jonah D. Hocum
- , Ian Linde
- & Grant D. Trobridge
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| Open AccessLocal Immune Stimulation by Intravesical Instillation of Baculovirus to Enable Bladder Cancer Therapy
- Wei Xia Ang
- , Ying Zhao
- & Shu Wang
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| Open AccessAnomalous uptake and circulatory characteristics of the plant-based small RNA MIR2911
- Jian Yang
- , Tremearne Hotz
- & Kendal D. Hirschi
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| Open AccessCancer-specific binary expression system activated in mice by bacteriophage HK022 Integrase
- Amer Elias
- , Itay Spector
- & Mikhail Kolot