G protein-coupled receptors articles within Scientific Reports

Featured

• Article
  10 May 2024 | Open Access

  Uncommon opsin’s retinal isomer is involved in mammalian sperm thermotaxis

  • Alexander Brandis
  • , Debarun Roy
  •  & Michael Eisenbach

• Article
  23 January 2024 | Open Access

  In vivo identification of Drosophila rhodopsin interaction partners by biotin proximity labeling

  • Nilofar Feizy
  • , Sarah Franziska Leuchtenberg
  •  & Armin Huber

• Article
  02 January 2024 | Open Access

  Arylsulfatases and neuraminidases modulate engagement of CCR5 by chemokines by removing key electrostatic interactions

  • Inês Pinheiro
  • , Nicolas Calo
  •  & Oliver Hartley

• Article
  26 September 2023 | Open Access

  Recovery of the histamine H₃ receptor activity lost in yeast cells through error-prone PCR and in vivo selection

  • Ayami Watanabe
  • , Ami Nakajima
  •  & Mitsunori Shiroishi

• Article
  29 January 2023 | Open Access

  Multiple opsins in a reef-building coral, Acropora millepora

  • Benjamin M. Mason
  • , Mitsumasa Koyanagi
  •  & Akihisa Terakita

• Article
  23 May 2022 | Open Access

  Yeast-based directed-evolution for high-throughput structural stabilization of G protein-coupled receptors (GPCRs)

  • M. Meltzer
  • , T. Zvagelsky
  •  & Stanislav Engel

• Article
  16 November 2021 | Open Access

  Understanding the role of the CB1 toggle switch in interaction networks using molecular dynamics simulation

  • Sangho Ji
  • , Wonjin Yang
  •  & Wookyung Yu

• Article
  15 November 2021 | Open Access

  Biophysical and functional characterization of the human TAS1R2 sweet taste receptor overexpressed in a HEK293S inducible cell line

  • Christine Belloir
  • , Marine Brulé
  •  & Loïc Briand

• Article
  27 October 2021 | Open Access

  Negative inotropic mechanisms of β-cardiotoxin in cardiomyocytes by depression of myofilament ATPase activity without activation of the classical β-adrenergic pathway

  • Tuchakorn Lertwanakarn
  • , Montamas Suntravat
  •  & Kittipong Tachampa

• Article
  08 July 2021 | Open Access

  Identification of V6.51L as a selectivity hotspot in stereoselective A_2B adenosine receptor antagonist recognition

  • Xuesong Wang
  • , Willem Jespers
  •  & Hugo Gutiérrez-de-Terán

• Article
  21 April 2021 | Open Access

  Directed evolution for high functional production and stability of a challenging G protein-coupled receptor

  • Yann Waltenspühl
  • , Jeliazko R. Jeliazkov
  •  & Andreas Plückthun

• Article
  12 April 2021 | Open Access

  Coevolution underlies GPCR-G protein selectivity and functionality

  • Min Jae Seo
  • , Joongyu Heo
  •  & Wookyung Yu

• Article
  14 January 2021 | Open Access

  A study of the dopamine transporter using the TRACT assay, a novel in vitro tool for solute carrier drug discovery

  • Hubert J. Sijben
  • , Julie J. E. van den Berg
  •  & Laura H. Heitman

• Article
  18 December 2020 | Open Access

  Identification and functional characterization of the first molluscan neuromedin U receptor in the slug, Deroceras reticulatum

  • Seung-Joon Ahn
  • , Rory J. Mc Donnell
  •  & Man-Yeon Choi

• Article
  14 December 2020 | Open Access

  Fluorescent ligands for dopamine D₂/D₃ receptors

  • Anni Allikalt
  • , Nirupam Purkayastha
  •  & Dorothee Weikert

• Article
  07 December 2020 | Open Access

  The G protein coupled receptor CXCR4 designed by the QTY code becomes more hydrophilic and retains cell signaling activity

  • Lotta Tegler
  • , Karolina Corin
  •  & Shuguang Zhang

• Article
  17 November 2020 | Open Access

  The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases

  • James L. J. Coleman
  • , Tony Ngo
  •  & Nicola J. Smith

• Article
  15 October 2020 | Open Access

  Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells

  • Thor C. Møller
  • , Mie F. Pedersen
  •  & Hans Bräuner-Osborne

• Article
  30 September 2020 | Open Access

  Identification of the dog orthologue of human MAS-related G protein coupled receptor X2 (MRGPRX2) essential for drug-induced pseudo-allergic reactions

  • Eri Hamamura-Yasuno
  • , Takuma Iguchi
  •  & Kazuhiko Mori

• Article
  01 July 2020 | Open Access

  Ste2 receptor-mediated chemotropism of Fusarium graminearum contributes to its pathogenicity against wheat

  • Pooja S. Sridhar
  • , Daria Trofimova
  •  & Michele C. Loewen

• Article
  15 June 2020 | Open Access

  The non-visual opsins expressed in deep brain neurons projecting to the retina in lampreys

  • Emi Kawano-Yamashita
  • , Mitsumasa Koyanagi
  •  & Akihisa Terakita

• Article
  04 June 2020 | Open Access

  Vasopressin receptor 2 mutations in the nephrogenic syndrome of inappropriate antidiuresis show different mechanisms of constitutive activation for G protein coupled receptors

  • Vanessa Vezzi
  • , Caterina Ambrosio
  •  & Susanna Cotecchia

• Article
  29 April 2020 | Open Access

  N-glycosylation of α_1D-adrenergic receptor N-terminal domain is required for correct trafficking, function, and biogenesis

  • Eric M. Janezic
  • , Sophia My-Linh Lauer
  •  & Chris Hague

• Article
  27 March 2020 | Open Access

  N-Phenethyl Substitution in 14-Methoxy-N-methylmorphinan-6-ones Turns Selective µ Opioid Receptor Ligands into Dual µ/δ Opioid Receptor Agonists

  • Maria Dumitrascuta
  • , Marcel Bermudez
  •  & Mariana Spetea

• Article
  01 October 2019 | Open Access

  Scribble co-operatively binds multiple α_1D-adrenergic receptor C-terminal PDZ ligands

  • Eric M. Janezic
  • , Dorathy-Ann Harris
  •  & Chris Hague

• Article
  11 June 2019 | Open Access

  Dual binding mode of “bitter sugars” to their human bitter taste receptor target

  • Fabrizio Fierro
  • , Alejandro Giorgetti
  •  & Mercedes Alfonso-Prieto

• Article
  27 May 2019 | Open Access

  Probe dependency in the determination of ligand binding kinetics at a prototypical G protein-coupled receptor

  • Reggie Bosma
  • , Leigh A. Stoddart
  •  & Rob Leurs

• Article
  07 May 2019 | Open Access

  Cartography of rhodopsin-like G protein-coupled receptors across vertebrate genomes

  • Maiju Rinne
  • , Zia-Ur-Rehman Tanoli
  •  & Henri Xhaard

• Article
  21 February 2019 | Open Access

  Mutations in sigma 70 transcription factor improves expression of functional eukaryotic membrane proteins in Escherichia coli

  • Pablo Emiliano Tomatis
  • , Marco Schütz
  •  & Andreas Plückthun

• Article
  08 February 2019 | Open Access

  The in vivo specificity of synaptic Gβ and Gγ subunits to the α_2a adrenergic receptor at CNS synapses

  • Yun Young Yim
  • , Katherine M. Betke
  •  & Heidi E. Hamm

• Article
  24 January 2019 | Open Access

  Arrestin-1 engineering facilitates complex stabilization with native rhodopsin

  • Raphael S. Haider
  • , Florian Wilhelm
  •  & Martin K. Ostermaier

• Article
  15 November 2018 | Open Access

  Structural Basis for Binding of Allosteric Drug Leads in the Adenosine A₁ Receptor

  • Yinglong Miao
  • , Apurba Bhattarai
  •  & Lauren T. May

• Article
  10 July 2018 | Open Access

  Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics

  • Thor C. Møller
  • , Jerome Hottin
  •  & Julie Kniazeff

• Article
  25 May 2018 | Open Access

  Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor

  • Sébastien Igonet
  • , Claire Raingeval
  •  & Anass Jawhari

• Article
  02 May 2018 | Open Access

  DNA Methylation of T1R1 Gene in the Vegetarian Adaptation of Grass Carp Ctenopharyngodon idella

  • Wenjing Cai
  • , Shan He
  •  & Xiaochen Yuan

• Article
  23 February 2018 | Open Access

  An all-trans-retinal-binding opsin peropsin as a potential dark-active and light-inactivated G protein-coupled receptor

  • Takashi Nagata
  • , Mitsumasa Koyanagi
  •  & Akihisa Terakita

• Article
  23 February 2018 | Open Access

  Nanodelivery of a functional membrane receptor to manipulate cellular phenotype

  • Tommaso Patriarchi
  • , Ao Shen
  •  & Lin Tian

• Article
  13 February 2018 | Open Access

  Expression, Purification and Characterization of the Human Cannabinoid 1 Receptor

  • Srikrishnan Mallipeddi
  • , Nikolai Zvonok
  •  & Alexandros Makriyannis

• Article
  19 January 2018 | Open Access

  The action of a negative allosteric modulator at the dopamine D₂ receptor is dependent upon sodium ions

  • Christopher J. Draper-Joyce
  • , Ravi Kumar Verma
  •  & J. Robert Lane

• Article
  05 December 2017 | Open Access

  The orientation and stability of the GPCR-Arrestin complex in a lipid bilayer

  • Dali Wang
  • , Hua Yu
  •  & Chen Song

• Article
  29 November 2017 | Open Access

  DHHC5-mediated palmitoylation of S1P receptor subtype 1 determines G-protein coupling

  • Shaymaa Mohamed Mohamed Badawy
  • , Taro Okada
  •  & Shun-ichi Nakamura

• Article
  23 October 2017 | Open Access

  Identification of a Different Agonist-Binding Site and Activation Mechanism of the Human P2Y₁ Receptor

  • Yang Li
  • , Can Yin
  •  & Jianping Lin

• Article
  28 September 2017 | Open Access

  The Role of Ubiquitination and Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate in the Degradation of the Adrenomedullin Type I Receptor

  • Benoît T. Roux
  • , Claudia C. Bauer
  •  & Graeme S. Cottrell

• Article
  11 September 2017 | Open Access

  Flavonoid allosteric modulation of mutated visual rhodopsin associated with retinitis pigmentosa

  • María Guadalupe Herrera-Hernández
  • , Eva Ramon
  •  & Pere Garriga

• Article
  10 August 2017 | Open Access

  The Bitter Taste Receptor TAS2R16 Achieves High Specificity and Accommodates Diverse Glycoside Ligands by using a Two-faced Binding Pocket

  • Anu Thomas
  • , Chidananda Sulli
  •  & Joseph B. Rucker

• Article
  08 August 2017 | Open Access

  Determination of the endothelin-1 recognition sites of endothelin receptor type A by the directed-degeneration method

  • Seong-Gu Han
  • , Sanghwan Ko
  •  & Yeon Gyu Yu

• Article
  04 August 2017 | Open Access

  Drosophila melanogaster rhodopsin Rh7 is a UV-to-visible light sensor with an extraordinarily broad absorption spectrum

  • Kazumi Sakai
  • , Kei Tsutsui
  •  & Yoshinori Shichida

• Article
  14 July 2017 | Open Access

  Conformational Transitions of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor, a Human Class B GPCR

  • Chenyi Liao
  • , Xiaochuan Zhao
  •  & Jianing Li

• Article
  11 July 2017 | Open Access

  All muscarinic acetylcholine receptors (M₁-M₅) are expressed in murine brain microvascular endothelium

  • Beatrice Mihaela Radu
  • , Antonio Marco Maria Osculati
  •  & Paolo Francesco Fabene

• Article
  16 June 2017 | Open Access

  Qualifying a eukaryotic cell-free system for fluorescence based GPCR analyses

  • Anne Zemella
  • , Solveig Grossmann
  •  & Stefan Kubick