DNA damage response articles within Scientific Reports

Featured

• Article
  04 March 2024 | Open Access

  Trypanosoma cruzi infection induces DNA double-strand breaks and activates DNA damage response pathway in host epithelial cells

  • Raul Alexander Gonzáles-Córdova
  • , Thamires Rossi dos Santos
  •  & Munira Muhammad Abdel Baqui

• Article
  19 December 2023 | Open Access

  Targeted inhibition of the ATR/CHK1 pathway overcomes resistance to olaparib and dysregulates DNA damage response protein expression in BRCA2^MUT ovarian cancer cells

  • Łukasz Biegała
  • , Arkadiusz Gajek
  •  & Aneta Rogalska

• Article
  20 July 2023 | Open Access

  An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage

  • Michael Agrez
  • , Mark Stephen Rybchyn
  •  & Laura Gallagher

• Article
  12 January 2023 | Open Access

  A non-catalytic N-terminus domain of WRN prevents mitotic telomere deprotection

  • Diana Romero-Zamora
  •  & Makoto T. Hayashi

• Article
  18 June 2022 | Open Access

  Polyphenols from persimmon fruit attenuate acetaldehyde-induced DNA double-strand breaks by scavenging acetaldehyde

  • Kenichiro Matsuzaki
  • , Kenji Kumatoriya
  •  & Miki Shinohara

• Article
  15 July 2021 | Open Access

  A simple microscopy setup for visualizing cellular responses to DNA damage at particle accelerator facilities

  • Haibin Qian
  • , Ron A. Hoebe
  •  & Przemek M. Krawczyk

• Article
  21 June 2021 | Open Access

  A small RNA regulates pprM, a modulator of pleiotropic proteins promoting DNA repair, in Deinococcus radiodurans under ionizing radiation

  • Jordan K. Villa
  • , Runhua Han
  •  & Lydia M. Contreras

• Article
  03 December 2020 | Open Access

  Exploring the effect of UV-C radiation on earthworm and understanding its genomic integrity in the context of H2AX expression

  • Karthikeyan Subbiahanadar Chelladurai
  • , Jackson Durairaj Selvan Christyraj
  •  & Johnson Retnaraj Samuel Selvan Christyraj

• Article
  10 November 2020 | Open Access

  Antibiotic-induced DNA damage results in a controlled loss of pH homeostasis and genome instability

  • James Alexander Booth
  • , Mário Špírek
  •  & Magnar Bjørås

• Article
  22 October 2020 | Open Access

  Maximized quantitative phosphoproteomics allows high confidence dissection of the DNA damage signaling network

  • Vitor Marcel Faca
  • , Ethan J. Sanford
  •  & Marcus B. Smolka

• Article
  18 June 2020 | Open Access

  Antitumor effect of a WEE1 inhibitor and potentiation of olaparib sensitivity by DNA damage response modulation in triple-negative breast cancer

  • Dong-Hyeon Ha
  • , Ahrum Min
  •  & Seock-Ah Im

• Article
  14 April 2020 | Open Access

  Fluid shear stress coupled with narrow constrictions induce cell type-dependent morphological and molecular changes in SK-BR-3 and MDA-MB-231 cells

  • Hamizah Ahmad Cognart
  • , Jean-Louis Viovy
  •  & Catherine Villard

• Article
  31 March 2020 | Open Access

  Podocyte-targeted Heme Oxygenase (HO)-1 overexpression exacerbates age-related pathology in the rat kidney

  • Elpida Poulaki
  • , Maria G. Detsika
  •  & Hariklia Gakiopoulou

• Article
  17 February 2020 | Open Access

  trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop

  • Yusuke Hirata
  • , Aya Inoue
  •  & Atsushi Matsuzawa

• Article
  07 February 2020 | Open Access

  Quantification of DNA Double Strand Breaks and Oxidation Response in Children and Adults Undergoing Dental CBCT Scan

  • Niels Belmans
  • , Liese Gilles
  •  & E. Embrechts

• Article
  10 October 2019 | Open Access

  DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G₂-checkpoint in S-phase irradiated cells

  • Emil Mladenov
  • , Xiaoxiang Fan
  •  & George Iliakis

• Article
  03 October 2019 | Open Access

  HERC2 regulates RPA2 by mediating ATR-induced Ser33 phosphorylation and ubiquitin-dependent degradation

  • Yongqiang Lai
  • , Mingzhang Zhu
  •  & Tomohiko Ohta

• Article
  30 September 2019 | Open Access

  Investigation of the core binding regions of human Werner syndrome and Fanconi anemia group J helicases on replication protein A

  • Gyuho Yeom
  • , Jinwoo Kim
  •  & Chin-Ju Park

• Article
  12 July 2019 | Open Access

  Fast dose fractionation using ultra-short laser accelerated proton pulses can increase cancer cell mortality, which relies on functional PARP1 protein

  • E. Bayart
  • , A. Flacco
  •  & V. Malka

• Article
  24 June 2019 | Open Access

  Radiation-Induced Bystander Effect is Mediated by Mitochondrial DNA in Exosome-Like Vesicles

  • Kentaro Ariyoshi
  • , Tomisato Miura
  •  & Mitsuaki Yoshida

• Article
  19 June 2019 | Open Access

  PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1

  • Haihong Guo
  • , Fabian Treude
  •  & Jörg Hartkamp

• Article
  25 April 2019 | Open Access

  The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair

  • Steven E. Guard
  • , Zachary C. Poss
  •  & William M. Old

• Article
  01 April 2019 | Open Access

  Osteogenic differentiation of skeletal muscle progenitor cells is activated by the DNA damage response

  • M. Rosina
  • , F. Langone
  •  & G. Cesareni

• Article
  19 March 2019 | Open Access

  TLP-mediated global transcriptional repression after double-strand DNA breaks slows down DNA repair and induces apoptosis

  • Hidefumi Suzuki
  • , Mayumi Okamoto-Katsuyama
  •  & Yuki Yamaguchi

• Article
  28 February 2019 | Open Access

  Genotoxic stress increases cytoplasmic mitochondrial DNA editing by human APOBEC3 mutator enzymes at a single cell level

  • Bianka Mussil
  • , Rodolphe Suspène
  •  & Jean-Pierre Vartanian

• Article
  22 February 2019 | Open Access

  Increased susceptibility of airway epithelial cells from ataxia-telangiectasia to S. pneumoniae infection due to oxidative damage and impaired innate immunity

  • Abrey J. Yeo
  • , Anna Henningham
  •  & Martin F. Lavin

• Article
  24 January 2019 | Open Access

  Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer’s disease in old Bmi1+/− mice

  • Jida El Hajjar
  • , Wassim Chatoo
  •  & Gilbert Bernier

• Article
  23 January 2019 | Open Access

  Three Prime Repair Exonuclease 1 (TREX1) expression correlates with cervical cancer cells growth in vitro and disease progression in vivo

  • Bruna Prati
  • , Walason da Silva Abjaude
  •  & Enrique Boccardo

• Article
  11 October 2018 | Open Access

  Effects of Thymoquinone on radiation enteritis in mice

  • Qinlian Hou
  • , Linlin Liu
  •  & Deguan Li

• Article
  18 September 2018 | Open Access

  Knock-down of AHCY and depletion of adenosine induces DNA damage and cell cycle arrest

  • Lucija Belužić
  • , Ivana Grbeša
  •  & Oliver Vugrek

• Article
  18 July 2018 | Open Access

  MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites

  • Sugiko Watanabe
  • , Makoto Iimori
  •  & Yoshihiko Maehara

• Article
  09 July 2018 | Open Access

  Dynamic behavior of DNA topoisomerase IIβ in response to DNA double-strand breaks

  • Keiko Morotomi-Yano
  • , Shinta Saito
  •  & Ken-ichi Yano

• Article
  04 July 2018 | Open Access

  Reversible mislocalization of a disease-associated MRE11 splice variant product

  • Andrea J. Hartlerode
  • , Joshua A. Regal
  •  & David O. Ferguson

• Article
  22 June 2018 | Open Access

  LIM Protein Ajuba associates with the RPA complex through direct cell cycle-dependent interaction with the RPA70 subunit

  • Sandy Fowler
  • , Pascal Maguin
  •  & Diego Loayza

• Article
  21 May 2018 | Open Access

  The live cell DNA stain SiR-Hoechst induces DNA damage responses and impairs cell cycle progression

  • Onur Sen
  • , Adrian T. Saurin
  •  & Jonathan M. G. Higgins

• Article
  29 March 2018 | Open Access

  Recruitment kinetics of the homologous recombination pathway in procyclic forms of Trypanosoma brucei after ionizing radiation treatment

  • Paula Andrea Marin
  • , Marcelo Santos da Silva
  •  & Maria Carolina Elias

• Article
  19 March 2018 | Open Access

  High yield bacterial expression, purification and characterisation of bioactive Human Tousled-like Kinase 1B involved in cancer

  • Siddhant Bhoir
  • , Althaf Shaik
  •  & Sivapriya Kirubakaran

• Article
  07 March 2018 | Open Access

  DNA damage induces a SAMHD1-mediated block to the infection of macrophages by HIV-1

  • Paula Jáuregui
  •  & Nathaniel R. Landau

• Article
  08 February 2018 | Open Access

  In Silico Non-Homologous End Joining Following Ion Induced DNA Double Strand Breaks Predicts That Repair Fidelity Depends on Break Density

  • N. T. Henthorn
  • , J. W. Warmenhoven
  •  & M. J. Merchant

• Article
  02 February 2018 | Open Access

  hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage

  • Alexandre Cloutier
  • , Lulzim Shkreta
  •  & Benoit Chabot

• Article
  20 December 2017 | Open Access

  p53 and cyclin G cooperate in mediating genome stability in somatic cells of Drosophila

  • Fabienne E. Bayer
  • , Mirjam Zimmermann
  •  & Anja C. Nagel

• Article
  01 December 2017 | Open Access

  Hypersensitivity of BRCA2 deficient cells to rosemary extract explained by weak PARP inhibitory activity

  • Cathy Su
  • , Jeffrey P. Gius
  •  & Takamitsu A. Kato

• Article
  30 November 2017 | Open Access

  Protein-lysine methyltransferases G9a and GLP1 promote responses to DNA damage

  • Vasudeva Ginjala
  • , Lizahira Rodriguez-Colon
  •  & Shridar Ganesan

• Article
  10 November 2017 | Open Access

  Tumor suppressor NPRL2 induces ROS production and DNA damage response

  • Yinxing Ma
  • , Licia Silveri
  •  & Svetlana Dokudovskaya

• Article
  07 September 2017 | Open Access

  Biomass burning in the Amazon region causes DNA damage and cell death in human lung cells

  • Nilmara de Oliveira Alves
  • , Alexandre Teixeira Vessoni
  •  & Silvia Regina Batistuzzo de Medeiros

• Article
  25 August 2017 | Open Access

  A missense MT-ND5 mutation in differentiated Parkinson Disease cytoplasmic hybrid induces ROS-dependent DNA Damage Response amplified by DROSHA

  • Daniela Pignataro
  • , Sofia Francia
  •  & Alessandra Montecucco

• Article
  19 June 2017 | Open Access

  Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation

  • Masayuki Hatanaka
  • , Emily Anderson-Baucum
  •  & Emily K. Sims

• Article
  07 June 2017 | Open Access

  Comparison of Different Drying Methods for Recovery of Mushroom DNA

  • Shouxian Wang
  • , Yu Liu
  •  & Jianping Xu

• Article
  08 May 2017 | Open Access

  Regulation of CHK1 by mTOR contributes to the evasion of DNA damage barrier of cancer cells

  • Xinhui Zhou
  • , Weijin Liu
  •  & Changxian Shen

• Article
  20 April 2017 | Open Access

  Red light improves spermatozoa motility and does not induce oxidative DNA damage

  • Daryl Preece
  • , Kay W. Chow
  •  & Michael W. Berns