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| Open AccessDirected evolution for high functional production and stability of a challenging G protein-coupled receptor
- Yann Waltenspühl
- , Jeliazko R. Jeliazkov
- & Andreas Plückthun
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| Open AccessA rebinding-assay for measuring extreme kinetics using label-free biosensors
- John G. Quinn
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| Open AccessEstradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors
- Philipp Rühl
- , Anna Scotto Rosato
- & Christian Grimm
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| Open AccessFirst observation of seasonal variations in the meat and co-products of the snow crab (Chionoecetes opilio) in the Barents Sea
- Runar Gjerp Solstad
- , Alexandre Descomps
- & Ragnhild Dragøy Whitaker
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| Open AccessStability of uniformly labeled (13C and 15N) cytochrome c and its L94G mutant
- Abdullah Naiyer
- , Bushra Khan
- & Faizan Ahmad
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| Open AccessCharacterization of design grammar of peptides for regulating liquid droplets and aggregates of FUS
- Kiyoto Kamagata
- , Rika Chiba
- & Tomoshi Kameda
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| Open AccessAnalysis of biomolecules in cochineal dyed archaeological textiles by surface-enhanced Raman spectroscopy
- F. Celis
- , C. Segura
- & S. Sanchez-Cortes
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| Open AccessEffects of high-intensity interval training in more or less active mice on biomechanical, biophysical and biochemical bone parameters
- Emanuel E. C. Polisel
- , Wladimir R. Beck
- & Fúlvia B. Manchado-Gobatto
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| Open AccessCharacteristics of bilirubin photochemical changes under green light-emitting diodes in humans compared with animal species
- Kohichiroh Nii
- , Hitoshi Okada
- & Takashi Kusaka
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| Open AccessLigand modulation of the conformational dynamics of the A2A adenosine receptor revealed by single-molecule fluorescence
- Dennis D. Fernandes
- , Chris Neale
- & Claudiu C. Gradinaru
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| Open AccessHyperpolarized 13C-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma
- Mor Mishkovsky
- , Olga Gusyatiner
- & Monika E. Hegi
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| Open AccessCryptic-site binding mechanism of medium-sized Bcl-xL inhibiting compounds elucidated by McMD-based dynamic docking simulations
- Gert-Jan Bekker
- , Ikuo Fukuda
- & Narutoshi Kamiya
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| Open AccessDetermination of the composition of heterogeneous binder solutions by surface plasmon resonance biosensing
- Jimmy Gaudreault
- , Benoît Liberelle
- & Gregory De Crescenzo
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| Open AccessAnalysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques
- Richard B. Gillis
- , Hodaya V. Solomon
- & Gary G. Adams
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| Open AccessNon-invasive skin sampling of tryptophan/kynurenine ratio in vitro towards a skin cancer biomarker
- Skaidre Jankovskaja
- , Johan Engblom
- & Sebastian Björklund
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| Open AccessInvestigating the influence of physiologically relevant hydrostatic pressure on CHO cell batch culture
- Menglin Shang
- , Taehong Kwon
- & Jongyoon Han
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| Open AccesspH-controlled stacking direction of the β-strands in peptide fibrils
- Wei-Hsuan Tseng
- , Szu-Hua Chen
- & Hirotsugu Hiramatsu
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| Open AccessBiochemical and biophysical characterization of the main protease, 3-chymotrypsin-like protease (3CLpro) from the novel coronavirus SARS-CoV 2
- Juliana C. Ferreira
- & Wael M. Rabeh
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| Open AccessBioluminescent detection of isothermal DNA amplification in microfluidic generated droplets and artificial cells
- Patrick Hardinge
- , Divesh K. Baxani
- & Oliver K. Castell
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| Open AccessNew information of dopaminergic agents based on quantum chemistry calculations
- Guillermo Goode-Romero
- , Ulrika Winnberg
- & Ana Martínez
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| Open AccessLocal environment effects on charged mutations for developing aggregation-resistant monoclonal antibodies
- Jihyeon Lee
- , Song-Ho Chong
- & Sihyun Ham
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| Open AccessComparing the permeability of human and porcine small intestinal mucus for particle transport studies
- Lukasz Krupa
- , Balazs Bajka
- & Adam Macierzanka
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| Open AccessIn situ formation of photoactive B-ring reduced chlorophyll isomer in photosynthetic protein LH2
- Yoshitaka Saga
- , Yuji Otsuka
- & Hitoshi Tamiaki
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| Open AccessThermodynamic analysis of cooperative ligand binding by the ATP-binding DNA aptamer indicates a population-shift binding mechanism
- Sladjana Slavkovic
- , Yanrui Zhu
- & Philip E. Johnson
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| Open AccessSpecifically bound BZIP transcription factors modulate DNA supercoiling transitions
- Johanna Hörberg
- & Anna Reymer
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| Open AccessModified aptamers as reagents to characterize recombinant human erythropoietin products
- Wojciech Jankowski
- , H. A. Daniel Lagassé
- & Zuben E. Sauna
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| Open AccessProtein conformational entropy is not slaved to water
- Bryan S. Marques
- , Matthew A. Stetz
- & Nathaniel V. Nucci
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| Open AccessThe structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics
- Enea Sancho-Vaello
- , David Gil-Carton
- & Kornelius Zeth
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| Open AccessThe structural role of osteocalcin in bone biomechanics and its alteration in Type-2 Diabetes
- Mahdi Tavakol
- & Ted J. Vaughan
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| Open AccessThermostability of a recombinant G protein-coupled receptor expressed at high level in mammalian cell culture
- Alexei Yeliseev
- , Arjen van den Berg
- & Jonathan Zmuda
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| Open AccessMembrane stiffness and myelin basic protein binding strength as molecular origin of multiple sclerosis
- Benjamin Krugmann
- , Aurel Radulescu
- & Andreas M. Stadler
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| Open AccessSaturation transfer difference NMR on the integral trimeric membrane transport protein GltPh determines cooperative substrate binding
- Jenny L. Hall
- , Azmat Sohail
- & Fraser MacMillan
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| Open AccessDependence of DNA length on binding affinity between TrpR and trpO of DNA
- Nobuo Shimamoto
- , Mikito Toda
- & Jun-ichi Tomizawa
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| Open AccessStability and robustness of asymptotic autocatalytic systems
- Sohyoun Yun-Cárcamo
- , Sebastián Carrasco
- & Juan Alejandro Valdivia
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| Open AccessAutomated AFM analysis of DNA bending reveals initial lesion sensing strategies of DNA glycosylases
- Disha M. Bangalore
- , Hannah S. Heil
- & Ingrid Tessmer
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| Open AccessStructural analysis of a new carotenoid-binding protein: the C-terminal domain homolog of the OCP
- Maria Agustina Dominguez-Martin
- , Michal Hammel
- & Cheryl A. Kerfeld
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| Open AccessFlexible ZnO-mAb nanoplatforms for selective peripheral blood mononuclear cell immobilization
- K. Sowri Babu
- , Pedro F. Pinheiro
- & Marta M. Alves
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| Open AccessGallic acid oxidation products alter the formation pathway of insulin amyloid fibrils
- Andrius Sakalauskas
- , Mantas Ziaunys
- & Vytautas Smirnovas
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| Open AccessChanges in γH2AX and H4K16ac levels are involved in the biochemical response to a competitive soccer match in adolescent players
- Katarzyna Kozioł
- , Jacek Zebrowski
- & Aleksandra Kwiatkowska
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| Open AccessGeneration of interconnected vesicles in a liposomal cell model
- Baharan Ali Doosti
- , Daniel Fjällborg
- & Tatsiana Lobovkina
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| Open AccessThe chirality origin of retinal-carotenoid complex in gloeobacter rhodopsin: a temperature-dependent excitonic coupling
- Sankar Jana
- , Kwang-Hwan Jung
- & Mordechai Sheves
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| Open AccessOral Phyto-thymol ameliorates the stress induced IBS symptoms
- Selvaraj Subramaniyam
- , Shuyou Yang
- & Sanjib Bhattacharyya
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| Open AccessInsights on small molecule binding to the Hv1 proton channel from free energy calculations with molecular dynamics simulations
- Victoria T. Lim
- , Andrew D. Geragotelis
- & Douglas J. Tobias
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| Open AccessIdentification and characterization of cytosolic malate dehydrogenase from the liver fluke Fasciola gigantica
- Purna Bahadur Chetri
- , Rohit Shukla
- & Timir Tripathi
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| Open AccessStructure and mechanism of potent bifunctional β-lactam- and homoserine lactone-degrading enzymes from marine microorganisms
- Christopher Selleck
- , Marcelo Monteiro Pedroso
- & Gerhard Schenk
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| Open AccessSpecific localisation of ions in bacterial membranes unravels physical mechanism of effective bacteria killing by sanitiser
- Judith Thoma
- , Wasim Abuillan
- & Motomu Tanaka
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| Open AccessProbing of carotenoid-tryptophan hydrogen bonding dynamics in the single-tryptophan photoactive Orange Carotenoid Protein
- Eugene G. Maksimov
- , Elena A. Protasova
- & Thomas Friedrich
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| Open AccessBlood pressure-lowering effects of a Bowman-Birk inhibitor and its derived peptides in normotensive and hypertensive rats
- Maria Alzira Garcia de Freitas
- , Nathalia Oda Amaral
- & Sonia Maria de Freitas
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| Open AccessRole of the activation peptide in the mechanism of protein C activation
- Bosko M. Stojanovski
- , Leslie A. Pelc
- & Enrico Di Cera