Featured
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Outlook |
AI assistance for planning cancer treatment
Armed with the right data, advances in machine learning could help oncologists to home in quickly on the best treatment strategies for their patients.
- Michael Eisenstein
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News Explainer |
Who owns your voice? Scarlett Johansson OpenAI complaint raises questions
In the age of artificial intelligence, situations are emerging that challenge the laws over rights to a persona.
- Nicola Jones
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Article
| Open AccessThe complete sequence and comparative analysis of ape sex chromosomes
Reference assemblies of great ape sex chromosomes show that Y chromosomes are more variable in size and sequence than X chromosomes and provide a resource for studies on human evolution and conservation genetics of non-human apes.
- Kateryna D. Makova
- , Brandon D. Pickett
- & Adam M. Phillippy
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Correspondence |
Anglo-American bias could make generative AI an invisible intellectual cage
- Queenie Luo
- & Michael Puett
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News Feature |
The AI revolution is coming to robots: how will it change them?
The melding of artificial intelligence and robotics could catapult both fields to new heights.
- Elizabeth Gibney
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Nature Podcast |
Audio long read: How does ChatGPT ‘think’? Psychology and neuroscience crack open AI large language models
To understand the 'brains' of LLMs, researchers are attempting to reverse-engineering artificial intelligence systems.
- Matthew Hutson
- & Benjamin Thompson
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News |
Superstar porous materials get salty thanks to computer simulations
Model predicts the structure of previously elusive compounds with practical applications.
- Ariana Remmel
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Editorial |
AlphaFold3 — why did Nature publish it without its code?
Criticism of our decision to publish AlphaFold3 raises important questions. We welcome readers’ views.
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News & Views |
AI networks reveal how flies find a mate
Artificial neural networks that model the visual system of a male fruit fly can accurately predict the insect’s behaviour in response to seeing a potential mate — paving the way for the building of more complex models of brain circuits.
- Pavan Ramdya
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News |
China’s ChatGPT: why China is building its own AI chatbots
ChatGLM is one of hundreds of AI language models being developed for the Chinese language. It comes close to ChatGPT on many measures, say its creators.
- Celeste Biever
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Article
| Open AccessMolecular mechanism of choline and ethanolamine transport in humans
Structural analysis of the human choline and ethanolamine transporters FLVCR1 and FLVCR2 clarifies the mechanisms of transport, the conformational dynamics of these proteins and the disease-associated mutations that interfere with these processes.
- Keiken Ri
- , Tsai-Hsuan Weng
- & Schara Safarian
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News |
First ‘bilingual’ brain-reading device decodes Spanish and English words
Artificial-intelligence system allows a man who cannot speak coherently to have a conversation in the language of his choice.
- Amanda Heidt
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Technology Feature |
DeepLabCut: the motion-tracking tool that went viral
Mackenzie and Alexander Mathis were still early in their careers when their software created a sensation. Now they’re using it to support other young scientists.
- Jyoti Madhusoodanan
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World View |
Why mathematics is set to be revolutionized by AI
Cheap data and the absence of coincidences make maths an ideal testing ground for AI-assisted discovery — but only humans will be able to tell good conjectures from bad ones.
- Thomas Fink
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News Feature |
How does ChatGPT ‘think’? Psychology and neuroscience crack open AI large language models
Researchers are striving to reverse-engineer artificial intelligence and scan the ‘brains’ of LLMs to see what they are doing, how and why.
- Matthew Hutson
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News Q&A |
The US Congress is taking on AI — this computer scientist is helping
Kiri Wagstaff, who temporarily shelved her academic career to provide advice on federal AI legislation, talks about life inside the halls of power.
- Nicola Jones
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Article |
Accurate structure prediction of biomolecular interactions with AlphaFold 3
- Josh Abramson
- , Jonas Adler
- & John M. Jumper
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Research Briefing |
‘Ghost roads’ could be the biggest direct threat to tropical forests
By using volunteers to map roads in forests across Borneo, Sumatra and New Guinea, an innovative study shows that existing maps of the Asia-Pacific region are rife with errors. It also reveals that unmapped roads are extremely common — up to seven times more abundant than mapped ones. Such ‘ghost roads’ are promoting illegal logging, mining, wildlife poaching and deforestation in some of the world’s biologically richest ecosystems.
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News |
Major AlphaFold upgrade offers boost for drug discovery
Latest version of the AI models how proteins interact with other molecules — but DeepMind restricts access to the tool.
- Ewen Callaway
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Article
| Open AccessThe intrinsic substrate specificity of the human tyrosine kinome
An atlas of the substrate specificities for the human tyrosine kinome reveals diversity of motif specificities and enables identification of kinase–substrate relationships and kinase regulation in phosphoproteomics experiments.
- Tomer M. Yaron-Barir
- , Brian A. Joughin
- & Jared L. Johnson
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Article
| Open AccessComputationally restoring the potency of a clinical antibody against Omicron
By demonstrating a computational approach to restore the clinical efficacy of a COVID-19 antibody, the potential to rapidly update clinical antibodies is explored.
- Thomas A. Desautels
- , Kathryn T. Arrildt
- & Daniel M. Faissol
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News |
Who’s making chips for AI? Chinese manufacturers lag behind US tech giants
Researchers in China say they are finding themselves five to ten years behind their US counterparts as export restrictions bite.
- Jonathan O'Callaghan
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News |
‘ChatGPT for CRISPR’ creates new gene-editing tools
Some of the AI-designed gene editors could be more versatile than those found in nature.
- Ewen Callaway
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Technology Feature |
85 million cells — and counting — at your fingertips
Chan Zuckerberg CELL by GENE Discover aims to be a one-stop shop for single-cell RNA sequencing data storage, access and analysis.
- Jeffrey M. Perkel
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News Feature |
Lethal AI weapons are here: how can we control them?
Autonomous weapons guided by artificial intelligence are already in use. Researchers, legal experts and ethicists are struggling with what should be allowed on the battlefield.
- David Adam
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Comment |
Will AI accelerate or delay the race to net-zero emissions?
As artificial intelligence transforms the global economy, researchers need to explore scenarios to assess how it can help, rather than harm, the climate.
- Amy Luers
- , Jonathan Koomey
- & Eric Horvitz
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Outlook |
AI’s keen diagnostic eye
Powered by deep-learning algorithms, artificial intelligence systems could replace agents such as chemicals currently used to augment medical scans.
- Neil Savage
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Nature Video |
AI and robotics demystify the workings of a fly's wing
New research unveils the workings of one of the most complex bio-mechanical structures in the natural world
- Dan Fox
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News |
AI traces mysterious metastatic cancers to their source
Algorithm examines images of metastatic cells to identify the location of the primary tumour.
- Smriti Mallapaty
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News |
AI now beats humans at basic tasks — new benchmarks are needed, says major report
Stanford University’s 2024 AI Index charts the meteoric rise of artificial-intelligence tools.
- Nicola Jones
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News |
Is ChatGPT corrupting peer review? Telltale words hint at AI use
A study of review reports identifies dozens of adjectives that could indicate text written with the help of chatbots.
- Dalmeet Singh Chawla
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Article
| Open AccessEmergence of fractal geometries in the evolution of a metabolic enzyme
Citrate synthase from the cyanobacterium Synechococcus elongatus is shown to self-assemble into Sierpiński triangles, a finding that opens up the possibility that other naturally occurring molecular-scale fractals exist.
- Franziska L. Sendker
- , Yat Kei Lo
- & Georg K. A. Hochberg
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Correspondence |
How to break big tech’s stranglehold on AI in academia
- Michał Woźniak
- & Paweł Ksieniewicz
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Comment |
AI can help to tailor drugs for Africa — but Africans should lead the way
Computational models that require very little data could transform biomedical and drug development research in Africa, as long as infrastructure, trained staff and secure databases are available.
- Gemma Turon
- , Mathew Njoroge
- & Kelly Chibale
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Technology Feature |
‘Without these tools, I’d be lost’: how generative AI aids in accessibility
A rush to place barriers around the use of artificial intelligence in academia could disproportionately affect those who stand to benefit most.
- Amanda Heidt
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Career Column |
Three ways ChatGPT helps me in my academic writing
Generative AI can be a valuable aid in writing, editing and peer review – if you use it responsibly, says Dritjon Gruda.
- Dritjon Gruda
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Career Feature |
Ready or not, AI is coming to science education — and students have opinions
As educators debate whether it’s even possible to use AI safely in research and education, students are taking a role in shaping its responsible use.
- Sarah Wells
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Research Briefing |
Artificial intelligence can provide accurate forecasts of extreme floods at global scale
Anthropogenic climate change is accelerating the hydrological cycle, causing an increase in the risk of flood-related disasters. A system that uses artificial intelligence allows the creation of reliable, global river flood forecasts, even in places where accurate local data are not available.
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Article
| Open AccessImmune microniches shape intestinal Treg function
Studies in mice show that effector T regulatory cells in the gut are most functional in the lamina propria, but this homeostatic niche is disrupted in inflammation, suggesting a spatial mechanism of tolerance to commensal microorganisms.
- Yisu Gu
- , Raquel Bartolomé-Casado
- & Fiona Powrie
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Article
| Open AccessThe complex polyploid genome architecture of sugarcane
We build a polyploid reference genome for hybrid sugarcane cultivar R570, improving on its current ‘mosaic monoploid’ representation, enabling fine-grain description of genome architecture and the exploration of candidate genes underlying the Bru1 brown rust resistance locus.
- A. L. Healey
- , O. Garsmeur
- & A. D’Hont
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Article
| Open AccessSingle-cell multiplex chromatin and RNA interactions in ageing human brain
We introduce multinucleic acid interaction mapping in single cells (MUSIC), for concurrent profiling of multiplex chromatin interactions, gene expression and RNA–chromatin associations within individual nuclei, as a tool for exploring chromatin architecture and transcription.
- Xingzhao Wen
- , Zhifei Luo
- & Sheng Zhong
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News Feature |
How AI is improving climate forecasts
Researchers are using various machine-learning strategies to speed up climate modelling, reduce its energy costs and hopefully improve accuracy.
- Carissa Wong
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News |
Google AI could soon use a person’s cough to diagnose disease
Machine-learning system trained on millions of human audio clips shows promise for detecting COVID-19 and tuberculosis.
- Mariana Lenharo
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Article
| Open AccessA distinct Fusobacterium nucleatum clade dominates the colorectal cancer niche
A study reveals that Fusobacterium nucleatum subspecies animalis is bifurcated into two distinct clades, and shows that only one of these dominates the colorectal cancer niche, probably through increased colonization of the human gastrointestinal tract.
- Martha Zepeda-Rivera
- , Samuel S. Minot
- & Christopher D. Johnston
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Correspondence |
Three reasons why AI doesn’t model human language
- Johan J. Bolhuis
- , Stephen Crain
- & Andrea Moro
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News |
‘A landmark moment’: scientists use AI to design antibodies from scratch
Modified protein-design tool could make it easier to tackle challenging drug targets — but AI antibodies are still a long way from reaching the clinic.
- Ewen Callaway
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News Feature |
AI image generators often give racist and sexist results: can they be fixed?
Researchers are tracing sources of racial and gender bias in images generated by artificial intelligence, and making efforts to fix them.
- Ananya
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News & Views |
Can lessons from infants solve the problems of data-greedy AI?
Words and images experienced by an infant wearing sensors during their daily life have led to efficient machine learning, pointing to the power of multimodal training signals and to the potentially exploitable statistics of real-life experience.
- Linda B. Smith
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Research Briefing |
‘Bandit’ algorithms help chemists to discover generally applicable conditions for reactions
In organic chemistry, finding conditions that enable a broad range of compounds to undergo a particular type of reaction is highly desirable. However, conventional methods for doing so consume a lot of time and reagents. A machine-learning method has been developed that overcomes these problems.
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